viral CD200
Virus-Cell InteractionsMembrane-Associated and Secreted Forms of the Rhesus Macaque Rhadinovirus-Encoded CD200 Homologue and Cellular CD200 Demonstrate Differential Effects on Rhesus Macaque CD200 Receptor Signaling and Regulation of Myeloid Cell ActivationViral CD200 homologues are encoded by Kaposi’s sarcoma-associated herpesvirus (KSHV) and the closely related rhesus macaque rhadinovirus (RRV). Though RRV viral CD200 (vCD200) has been examined, questions still exist in regard to the ability of this molecule to induce signaling via rhesus macaque CD200 receptor (CD200R) as well as the potential function of a secreted form of vCD200.