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transcriptional activation

  • Cellular RNA Helicase DHX9 Interacts with the Essential Epstein-Barr Virus (EBV) Protein SM and Restricts EBV Lytic Replication
    Virus-Cell Interactions
    Cellular RNA Helicase DHX9 Interacts with the Essential Epstein-Barr Virus (EBV) Protein SM and Restricts EBV Lytic Replication

    This study identifies an interaction between Epstein-Barr virus (EBV) SM protein and cellular helicase DHX9, exploring the roles that this interaction plays in viral infection and host defenses. Whereas most previous studies established DHX9 as a proviral factor, we demonstrate that DHX9 may act as an inhibitor of EBV virion production. DHX9 enhanced innate antiviral pathways active against EBV and was needed for maximal expression of...

    Wenmin Fu, Dinesh Verma, Ashlee Burton, Sankar Swaminathan
  • Virus-Cell Interactions
    The SWI/SNF Chromatin Regulator BRG1 Modulates the Transcriptional Regulatory Activity of the Epstein-Barr Virus DNA Polymerase Processivity Factor BMRF1
    Mei-Tzu Su, Ya-Ting Wang, Yen-Ju Chen, Su-Fang Lin, Ching-Hwa Tsai, Mei-Ru Chen
  • Open Access
    Pathogenesis and Immunity
    IRAV (FLJ11286), an Interferon-Stimulated Gene with Antiviral Activity against Dengue Virus, Interacts with MOV10
    Corey A. Balinsky, Hana Schmeisser, Alexandra I. Wells, Sundar Ganesan, Tengchuan Jin, Kavita Singh, Kathryn C. Zoon
  • Genome Replication and Regulation of Viral Gene Expression
    Identification of Novel Kaposi's Sarcoma-Associated Herpesvirus Orf50 Transcripts: Discovery of New RTA Isoforms with Variable Transactivation Potential
    Brian S. Wakeman, Yoshihiro Izumiya, Samuel H. Speck
  • Virus-Cell Interactions | Spotlight
    Human Cytomegalovirus Induces the Endoplasmic Reticulum Chaperone BiP through Increased Transcription and Activation of Translation by Using the BiP Internal Ribosome Entry Site
    Nicholas J. Buchkovich, Yongjun Yu, Francis J. Pierciey, James C. Alwine
  • Pathogenesis and Immunity | Spotlight
    Lambda Interferon Is the Predominant Interferon Induced by Influenza A Virus Infection In Vivo
    Nancy A. Jewell, Troy Cline, Sara E. Mertz, Sergey V. Smirnov, Emilio FlaƱo, Christian Schindler, Jessica L. Grieves, Russell K. Durbin, Sergei V. Kotenko, Joan E. Durbin
  • Pathogenesis and Immunity
    Hit-and-Run Stimulation: a Novel Concept To Reactivate Latent HIV-1 Infection without Cytokine Gene Induction
    Frank Wolschendorf, Alexandra Duverger, Jennifer Jones, Frederic H. Wagner, Jason Huff, William H. Benjamin, Michael S. Saag, Michael Niederweis, Olaf Kutsch
  • Virus-Cell Interactions
    Human Cytomegalovirus pUL83 Stimulates Activity of the Viral Immediate-Early Promoter through Its Interaction with the Cellular IFI16 Protein
    Ileana M. Cristea, Nathaniel J. Moorman, Scott S. Terhune, Christian D. Cuevas, Erin S. O'Keefe, Michael P. Rout, Brian T. Chait, Thomas Shenk
  • ERRATA
    Effect of the Internal Promoter on Insertional Gene Activation by Lentiviral Vectors with an Intact HIV Long Terminal Repeat
    Sean Knight, Marieke Bokhoven, Mary Collins, Yasuhiro Takeuchi
  • Gene Delivery
    Effect of the Internal Promoter on Insertional Gene Activation by Lentiviral Vectors with an Intact HIV Long Terminal Repeat
    Sean Knight, Marieke Bokhoven, Mary Collins, Yasuhiro Takeuchi

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