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stem cells

  • CD34<sup>+</sup> Hematopoietic Progenitor Cell Subsets Exhibit Differential Ability To Maintain Human Cytomegalovirus Latency and Persistence
    Virus-Cell Interactions
    CD34+ Hematopoietic Progenitor Cell Subsets Exhibit Differential Ability To Maintain Human Cytomegalovirus Latency and Persistence

    Human cytomegalovirus infection is associated with severe disease in transplant patients, and understanding how latency and reactivation occur in stem cell populations is essential to understand disease. CD34+ hematopoietic progenitor cells (HPCs) are a critical viral reservoir; however, these cells are a heterogeneous pool with donor-to-donor variation in functional, genetic, and phenotypic characteristics.

    ...
    Lindsey B. Crawford, Meaghan H. Hancock, Hillary M. Struthers, Daniel N. Streblow, Andrew D. Yurochko, Patrizia Caposio, Felicia D. Goodrum, Jay A. Nelson
  • Genome Replication and Regulation of Viral Gene Expression
    Quiescence Promotes Latent HIV Infection and Resistance to Reactivation from Latency with Histone Deacetylase Inhibitors
    Mark M. Painter, Thomas D. Zaikos, Kathleen L. Collins
  • Virus-Cell Interactions
    Human Cytomegalovirus Infection Causes Premature and Abnormal Differentiation of Human Neural Progenitor Cells
    Min Hua Luo, Holger Hannemann, Amit S. Kulkarni, Philip H. Schwartz, John M. O'Dowd, Elizabeth A. Fortunato
  • Pathogenesis and Immunity
    Neonatal Neural Progenitor Cells and Their Neuronal and Glial Cell Derivatives Are Fully Permissive for Human Cytomegalovirus Infection
    Min Hua Luo, Philip H. Schwartz, Elizabeth A. Fortunato
  • Vaccines and Antiviral Agents
    Cyclosporine Inhibits Mouse Cytomegalovirus Infection via a Cyclophilin-Dependent Pathway Specifically in Neural Stem/Progenitor Cells
    Hideya Kawasaki, Edward S. Mocarski, Isao Kosugi, Yoshihiro Tsutsui
  • Pathogenesis and Immunity
    Epstein-Barr Virus Infection of Langerhans Cell Precursors as a Mechanism of Oral Epithelial Entry, Persistence, and Reactivation
    Dennis M. Walling, Autumn J. Ray, Joan E. Nichols, Catherine M. Flaitz, C. Mark Nichols
  • GENE THERAPY
    Targeting c-Mpl for Revival of Human Immunodeficiency Virus Type 1-Induced Hematopoietic Inhibition When CD34+ Progenitor Cells Are Re-Engrafted into a Fresh Stromal Microenvironment In Vivo
    Prasad S. Koka, Christina M. R. Kitchen, Srinivasa T. Reddy
  • Pathogenesis and Immunity
    Human Immunodeficiency Virus Type 1 Infection of Human Brain-Derived Progenitor Cells
    Diane M. P. Lawrence, Linda C. Durham, Lynnae Schwartz, Pankaj Seth, Dragan Maric, Eugene O. Major
  • Virus-Cell Interactions
    New World Arenavirus Clade C, but Not Clade A and B Viruses, Utilizes α-Dystroglycan as Its Major Receptor
    Christina F. Spiropoulou, Stefan Kunz, Pierre E. Rollin, Kevin P. Campbell, Michael B. A. Oldstone
  • Virus-Cell Interactions
    Human Mast Cell Progenitors Can Be Infected by Macrophagetropic Human Immunodeficiency Virus Type 1 and Retain Virus with Maturation In Vitro
    Norbert Bannert, Michael Farzan, Daniel S. Friend, Hiroshi Ochi, Kursteen S. Price, Joseph Sodroski, Joshua A. Boyce

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