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Nipah virus

  • Henipavirus W Proteins Interact with 14-3-3 To Modulate Host Gene Expression
    Virus-Cell Interactions
    Henipavirus W Proteins Interact with 14-3-3 To Modulate Host Gene Expression

    Nipah virus (NiV) and Hendra virus (HeV), members of the Henipavirus genus, are recently emerged, highly lethal zoonotic pathogens that cause yearly outbreaks. NiV and HeV each encode a W protein that has roles in regulating host signaling pathways, including antagonism of the innate immune response. However, the mechanisms used by W to regulate these host responses are not clear. Here, characterization of the interaction of...

    Megan R. Edwards, Mikayla Hoad, Sofiya Tsimbalyuk, Andrea R. Menicucci, Ilhem Messaoudi, Jade K. Forwood, Christopher F. Basler
  • Tetherin Inhibits Nipah Virus but Not Ebola Virus Replication in Fruit Bat Cells
    Virus-Cell Interactions
    Tetherin Inhibits Nipah Virus but Not Ebola Virus Replication in Fruit Bat Cells

    Ebola virus and Nipah virus (EBOV and NiV) can cause fatal disease in humans. In contrast, infected fruit bats do not develop symptoms but can transmit the virus to humans. Why fruit bats but not humans control infection is largely unknown. Tetherin is an antiviral host cell protein and is counteracted by the EBOV glycoprotein in human cells. Here, employing model systems, we show that tetherin of fruit bats displays higher antiviral...

    Markus Hoffmann, Inga Nehlmeier, Constantin Brinkmann, Verena Krähling, Laura Behner, Anna-Sophie Moldenhauer, Nadine Krüger, Julia Nehls, Michael Schindler, Thomas Hoenen, Andrea Maisner, Stephan Becker, Stefan Pöhlmann
  • Virus-Cell Interactions
    Exploring the Human-Nipah Virus Protein-Protein Interactome
    Luis Martinez-Gil, Natalia M. Vera-Velasco, Ismael Mingarro
  • Virus-Cell Interactions
    Nipah and Hendra Virus Nucleoproteins Inhibit Nuclear Accumulation of Signal Transducer and Activator of Transcription 1 (STAT1) and STAT2 by Interfering with Their Complex Formation
    Akihiro Sugai, Hiroki Sato, Ikuyo Takayama, Misako Yoneda, Chieko Kai
  • Pathogenesis and Immunity
    Contribution of Human Lung Parenchyma and Leukocyte Influx to Oxidative Stress and Immune System-Mediated Pathology following Nipah Virus Infection
    Olivier Escaffre, Tais B. Saito, Terry L. Juelich, Tetsuro Ikegami, Jennifer K. Smith, David D. Perez, Colm Atkins, Corri B. Levine, Matthew B. Huante, Rebecca J. Nusbaum, Janice J. Endsley, Alexander N. Freiberg, Barry Rockx
  • Structure and Assembly
    Cytoplasmic Motifs in the Nipah Virus Fusion Protein Modulate Virus Particle Assembly and Egress
    Gunner P. Johnston, Erik M. Contreras, Jeffrey Dabundo, Bryce A. Henderson, Keesha M. Matz, Victoria Ortega, Alfredo Ramirez, Arnold Park, Hector C. Aguilar
  • Virus-Cell Interactions | Spotlight
    Chikungunya, Influenza, Nipah, and Semliki Forest Chimeric Viruses with Vesicular Stomatitis Virus: Actions in the Brain
    Anthony N. van den Pol, Guochao Mao, Anasuya Chattopadhyay, John K. Rose, John N. Davis
  • Pathogenesis and Immunity
    Novel Nipah Virus Immune-Antagonism Strategy Revealed by Experimental and Computational Study
    Jeremy Seto, Liang Qiao, Carolin A. Guenzel, Sa Xiao, Megan L. Shaw, Fernand Hayot, Stuart C. Sealfon
  • Genome Replication and Regulation of Viral Gene Expression
    Novel Phosphoprotein-Interacting Region in Nipah Virus Nucleocapsid Protein and Its Involvement in Viral Replication
    Mio Omi-Furutani, Misako Yoneda, Kentaro Fujita, Fusako Ikeda, Chieko Kai
  • Virus-Cell Interactions
    A Quantitative and Kinetic Fusion Protein-Triggering Assay Can Discern Distinct Steps in the Nipah Virus Membrane Fusion Cascade
    Hector C. Aguilar, Vanessa Aspericueta, Lindsey R. Robinson, Karen E. Aanensen, Benhur Lee

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