Nipah virus
Virus-Cell InteractionsRoles of Cholesterol in Early and Late Steps of the Nipah Virus Membrane Fusion CascadeCholesterol has been implicated in various steps of the viral life cycle for different enveloped viruses. Nipah virus (NiV) is a highly pathogenic enveloped virus in the Henipavirus genus within the Paramyxoviridae family, capable of causing a high mortality rate in humans and high morbidity in domestic and agriculturally important animals.
Virus-Cell InteractionsHenipavirus W Proteins Interact with 14-3-3 To Modulate Host Gene ExpressionNipah virus (NiV) and Hendra virus (HeV), members of the Henipavirus genus, are recently emerged, highly lethal zoonotic pathogens that cause yearly outbreaks. NiV and HeV each encode a W protein that has roles in regulating host signaling pathways, including antagonism of the innate immune response. However, the mechanisms used by W to regulate these host responses are not clear. Here, characterization of the interaction of...
Virus-Cell InteractionsTetherin Inhibits Nipah Virus but Not Ebola Virus Replication in Fruit Bat CellsEbola virus and Nipah virus (EBOV and NiV) can cause fatal disease in humans. In contrast, infected fruit bats do not develop symptoms but can transmit the virus to humans. Why fruit bats but not humans control infection is largely unknown. Tetherin is an antiviral host cell protein and is counteracted by the EBOV glycoprotein in human cells. Here, employing model systems, we show that tetherin of fruit bats displays higher antiviral...
- Virus-Cell InteractionsExploring the Human-Nipah Virus Protein-Protein Interactome
- Virus-Cell Interactions | SpotlightChikungunya, Influenza, Nipah, and Semliki Forest Chimeric Viruses with Vesicular Stomatitis Virus: Actions in the Brain
- Pathogenesis and ImmunityNovel Nipah Virus Immune-Antagonism Strategy Revealed by Experimental and Computational Study
- Genome Replication and Regulation of Viral Gene ExpressionNovel Phosphoprotein-Interacting Region in Nipah Virus Nucleocapsid Protein and Its Involvement in Viral Replication