Mutation, Missense

Vaccines and Antiviral Agents
High-Throughput Protein Engineering Improves the Antigenicity and Stability of Soluble HIV-1 Envelope Glycoprotein SOSIP Trimers
Jonathan T. Sullivan, Chidananda Sulli, Alberto Nilo, Anila Yasmeen, Gabriel Ozorowski, Rogier W. Sanders, Andrew B. Ward, P. J. Klasse, John P. Moore, Benjamin J. Doranz
Open Access

Vaccines and Antiviral Agents
Foot-and-Mouth Disease (FMD) Virus 3C Protease Mutant L127P: Implications for FMD Vaccine Development
Michael Puckette, Benjamin A. Clark, Justin D. Smith, Traci Turecek, Erica Martel, Lindsay Gabbert, Melia Pisano, William Hurtle, Juan M. Pacheco, José Barrera, John G. Neilan, Max Rasmussen
Virus-Cell Interactions
The K186E Amino Acid Substitution in the Canine Influenza Virus H3N8 NS1 Protein Restores Its Ability To Inhibit Host Gene Expression
Aitor Nogales, Caroline Chauché, Marta L. DeDiego, David J. Topham, Colin R. Parrish, Pablo R. Murcia, Luis Martínez-Sobrido
Free

Virus-Cell Interactions
Spontaneous Mutation at Amino Acid 544 of the Ebola Virus Glycoprotein Potentiates Virus Entry and Selection in Tissue Culture
John B. Ruedas, Jason T. Ladner, Chelsea R. Ettinger, Suryaram Gummuluru, Gustavo Palacios, John H. Connor
Pathogenesis and Immunity | Spotlight
Altered Receptor Specificity and Cell Tropism of D222G Hemagglutinin Mutants Isolated from Fatal Cases of Pandemic A(H1N1) 2009 Influenza Virus
Yan Liu, Robert A. Childs, Tatyana Matrosovich, Stephen Wharton, Angelina S. Palma, Wengang Chai, Rodney Daniels, Victoria Gregory, Jennifer Uhlendorff, Makoto Kiso, Hans-Dieter Klenk, Alan Hay, Ten Feizi, Mikhail Matrosovich
Virus-Cell Interactions
Pseudorevertants of a Semliki Forest Virus Fusion-Blocking Mutation Reveal a Critical Interchain Interaction in the Core Trimer
Catherine Y. Liu, Christen Besanceney, Yifan Song, Margaret Kielian
Genetic Diversity and Evolution
Tracking the Evolution of Multiple In Vitro Hepatitis C Virus Replicon Variants under Protease Inhibitor Selection Pressure by 454 Deep Sequencing
Thierry Verbinnen, Herwig Van Marck, Ina Vandenbroucke, Leen Vijgen, Marijke Claes, Tse-I Lin, Kenneth Simmen, Johan Neyts, Gregory Fanning, Oliver Lenz
Pathogenesis and Immunity
Mutation at a Single Position in the V2 Domain of the HIV-1 Envelope Protein Confers Neutralization Sensitivity to a Highly Neutralization-Resistant Virus
Sara M. O'Rourke, Becky Schweighardt, Pham Phung, Dora P. A. J. Fonseca, Karianne Terry, Terri Wrin, Faruk Sinangil, Phillip W. Berman
Virus-Cell Interactions
Mutations in the Stalk Region of the Measles Virus Hemagglutinin Inhibit Syncytium Formation but Not Virus Entry
Matthew K. Ennis, Chunling Hu, Shruthi K. Naik, Louay K. Hallak, Kah Whye Peng, Stephen J. Russell, David Dingli
Virus-Cell Interactions
PB2 and Hemagglutinin Mutations Are Major Determinants of Host Range and Virulence in Mouse-Adapted Influenza A Virus
Jihui Ping, Samar K. Dankar, Nicole E. Forbes, Liya Keleta, Yan Zhou, Shaun Tyler, Earl G. Brown

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