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morbillivirus

  • Open Access
    Comparison of the Immunogenicities and Cross-Lineage Efficacies of Live Attenuated Peste des Petits Ruminants Virus Vaccines PPRV/Nigeria/75/1 and PPRV/Sungri/96
    Vaccines and Antiviral Agents
    Comparison of the Immunogenicities and Cross-Lineage Efficacies of Live Attenuated Peste des Petits Ruminants Virus Vaccines PPRV/Nigeria/75/1 and PPRV/Sungri/96

    Despite the widespread use of live attenuated PPRV vaccines, this is the first systematic analysis of the immune response elicited in small ruminants. These data will help in the establishment of the immunological determinants of protection, an important step in the development of new vaccines, especially DIVA vaccines using alternative vaccination vectors. This study is also the first controlled test of the ability of the two major...

    Sophia Hodgson, Katy Moffat, Holly Hill, John T. Flannery, Simon P. Graham, Michael D. Baron, Karin E. Darpel
  • Open Access
    Structure-Guided Identification of a Nonhuman Morbillivirus with Zoonotic Potential
    Virus-Cell Interactions
    Structure-Guided Identification of a Nonhuman Morbillivirus with Zoonotic Potential

    A significant proportion of viral pandemics occur following zoonotic transmission events, where animal-associated viruses jump species into human populations. In order to provide forewarnings of the emergence of these viruses, it is necessary to develop a better understanding of what determines virus host range, often at the genetic and structural levels. In this study, we demonstrated that the small-ruminant morbillivirus, a close...

    Nurshariza Abdullah, James T. Kelly, Stephen C. Graham, Jamie Birch, Daniel Gonçalves-Carneiro, Tim Mitchell, Robin N. Thompson, Katrina A. Lythgoe, Nicola Logan, Margaret J. Hosie, Vassiliy N. Bavro, Brian J. Willett, Michael P. Heaton, Dalan Bailey
  • Regulatory Role of the Morbillivirus Attachment Protein Head-to-Stalk Linker Module in Membrane Fusion Triggering
    Virus-Cell Interactions
    Regulatory Role of the Morbillivirus Attachment Protein Head-to-Stalk Linker Module in Membrane Fusion Triggering
    Michael Herren, Neeta Shrestha, Marianne Wyss, Andreas Zurbriggen, Philippe Plattet
  • Virus-Cell Interactions
    Measles Virus Enters Breast and Colon Cancer Cell Lines through a PVRL4-Mediated Macropinocytosis Pathway
    Sebastien Delpeut, Gary Sisson, Karen M. Black, Christopher D. Richardson
  • Open Access
    Virus-Cell Interactions
    The Measles Virus Receptor SLAMF1 Can Mediate Particle Endocytosis
    Daniel Gonçalves-Carneiro, Jane A. McKeating, Dalan Bailey
  • Pathogenesis and Immunity | Spotlight
    Receptor (SLAM [CD150]) Recognition and the V Protein Sustain Swift Lymphocyte-Based Invasion of Mucosal Tissue and Lymphatic Organs by a Morbillivirus
    Veronika von Messling, Nicholas Svitek, Roberto Cattaneo
  • Genome Replication and Regulation of Viral Gene Expression
    Rational Attenuation of a Morbillivirus by Modulating the Activity of the RNA-Dependent RNA Polymerase
    David D. Brown, Bertus K. Rima, Ingrid V. Allen, Michael D. Baron, Ashley C. Banyard, Thomas Barrett, W. Paul Duprex
  • Pathogenesis and Immunity
    Inhibition of In Vitro Leukocyte Proliferation by Morbilliviruses
    J. Heaney, T. Barrett, S. L. Cosby
  • Virus-Cell Interactions
    Morbillivirus Downregulation of CD46
    Sareen E. Galbraith, Ashok Tiwari, Michael D. Baron, Brett T. Lund, Thomas Barrett, S. Louise Cosby
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