morbillivirus
Pathogenesis and Immunity | SpotlightC Protein Is Essential for Canine Distemper Virus Virulence and Pathogenicity in FerretsThe measles (MeV) and canine distemper (CDV) viruses express accessory proteins that regulate the host’s immune response and enhance replication. The MeV C protein is critical in preventing the generation of excess immunostimulatory double-stranded RNA.
Vaccines and Antiviral AgentsComparison of the Immunogenicities and Cross-Lineage Efficacies of Live Attenuated Peste des Petits Ruminants Virus Vaccines PPRV/Nigeria/75/1 and PPRV/Sungri/96Despite the widespread use of live attenuated PPRV vaccines, this is the first systematic analysis of the immune response elicited in small ruminants. These data will help in the establishment of the immunological determinants of protection, an important step in the development of new vaccines, especially DIVA vaccines using alternative vaccination vectors. This study is also the first controlled test of the ability of the two major...
Virus-Cell InteractionsStructure-Guided Identification of a Nonhuman Morbillivirus with Zoonotic PotentialA significant proportion of viral pandemics occur following zoonotic transmission events, where animal-associated viruses jump species into human populations. In order to provide forewarnings of the emergence of these viruses, it is necessary to develop a better understanding of what determines virus host range, often at the genetic and structural levels. In this study, we demonstrated that the small-ruminant morbillivirus, a close...
- Virus-Cell InteractionsThe Measles Virus Receptor SLAMF1 Can Mediate Particle Endocytosis
- Pathogenesis and Immunity | SpotlightReceptor (SLAM [CD150]) Recognition and the V Protein Sustain Swift Lymphocyte-Based Invasion of Mucosal Tissue and Lymphatic Organs by a Morbillivirus
- Genome Replication and Regulation of Viral Gene ExpressionRational Attenuation of a Morbillivirus by Modulating the Activity of the RNA-Dependent RNA Polymerase
- Pathogenesis and ImmunityInhibition of In Vitro Leukocyte Proliferation by Morbilliviruses
- Virus-Cell InteractionsMorbillivirus Downregulation of CD46
