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lectins

  • The High Content of Fructose in Human Semen Competitively Inhibits Broad and Potent Antivirals That Target High-Mannose Glycans
    Vaccines and Antiviral Agents
    The High Content of Fructose in Human Semen Competitively Inhibits Broad and Potent Antivirals That Target High-Mannose Glycans

    Biological secretions allow viruses to spread between individuals. Each type of secretion has a unique composition of proteins, salts, and sugars, which can affect the infectivity potential of the virus and inhibition of this process. Here, we describe HIV-1 infection and inhibition in whole human seminal plasma and a synthetic simulant that we formulated. We discovered that the sugar fructose in semen decreases the activity of a broad...

    Jacklyn Johnson, Manuel G. Flores, John Rosa, Changze Han, Alicia M. Salvi, Kris A. DeMali, Jennifer R. Jagnow, Amy Sparks, Hillel Haim
  • Erratum
    Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae
    Barry R. O'Keefe, Barbara Giomarelli, Dale L. Barnard, Shilpa R. Shenoy, Paul K. S. Chan, James B. McMahon, Kenneth E. Palmer, Brian W. Barnett, David K. Meyerholz, Christine L. Wohlford-Lenane, Paul B. McCray
  • Vaccines and Antiviral Agents
    Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae
    Barry R. O'Keefe, Barbara Giomarelli, Dale L. Barnard, Shilpa R. Shenoy, Paul K. S. Chan, James B. McMahon, Kenneth E. Palmer, Brian W. Barnett, David K. Meyerholz, Christine L. Wohlford-Lenane, Paul B. McCray
  • Virus-Cell Interactions
    Kaposi's Sarcoma-Associated Herpesvirus Lytic Switch Protein Stimulates DNA Binding of RBP-Jk/CSL To Activate the Notch Pathway
    Kyla Driscoll Carroll, Wei Bu, Diana Palmeri, Sophia Spadavecchia, Stephen J. Lynch, Salvatore A. E. Marras, Sanjay Tyagi, David M. Lukac
  • Structure and Assembly
    Lectin-Mediated Retention of p62 Facilitates p62-E1 Heterodimerization in Endoplasmic Reticulum of Semliki Forest Virus-Infected Cells
    Helena Andersson, Henrik Garoff
  • Virus-Cell Interactions
    Quantitative Expression and Virus Transmission Analysis of DC-SIGN on Monocyte-Derived Dendritic Cells
    Frédéric Baribaud, Stefan Pöhlmann, George Leslie, Frank Mortari, Robert W. Doms
  • Pathogenesis and Immunity
    The Lipopolysaccharide and β-1,3-Glucan Binding Protein Gene Is Upregulated in White Spot Virus-Infected Shrimp (Penaeus stylirostris)
    Michelle M. Roux, Arnab Pain, Kurt R. Klimpel, Arun K. Dhar
  • Virus-Cell Interactions
    C-Type Lectins DC-SIGN and L-SIGN Mediate Cellular Entry by Ebola Virus in cis and in trans
    Carmen P. Alvarez, Fátima Lasala, Jaime Carrillo, Oscar Muñiz, Angel L. Corbí, Rafael Delgado
  • Virus-Cell Interactions
    Functional Evaluation of DC-SIGN Monoclonal Antibodies Reveals DC-SIGN Interactions with ICAM-3 Do Not Promote Human Immunodeficiency Virus Type 1 Transmission
    Li Wu, Thomas D. Martin, Rosemay Vazeux, Derya Unutmaz, Vineet N. KewalRamani
  • Virus-Cell Interactions
    Expression of DC-SIGN by Dendritic Cells of Intestinal and Genital Mucosae in Humans and Rhesus Macaques
    Brian Jameson, Frédéric Baribaud, Stefan Pöhlmann, Darlene Ghavimi, Frank Mortari, Robert W. Doms, Akiko Iwasaki

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