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L2

  • Phosphorylation of Human Papillomavirus Type 16 L2 Contributes to Efficient Virus Infectious Entry
    Virus-Cell Interactions | Spotlight
    Phosphorylation of Human Papillomavirus Type 16 L2 Contributes to Efficient Virus Infectious Entry

    The papillomavirus L2 capsid protein plays an essential role in infectious entry, where it directs the successful trafficking of incoming viral genomes to the nucleus. However, nothing is known about how potential posttranslational modifications may affect different aspects of capsid assembly or infectious entry. In this study, we report the first phospho-specific modification of the BPV-1 and HPV-16 L2 capsid proteins. The phospho-...

    Justyna Broniarczyk, Paola Massimi, David Pim, Martina Bergant Marušič, Michael P. Myers, Robert L. Garcea, Lawrence Banks
  • Vaccines and Antiviral Agents
    Minor Capsid Protein L2 Polytope Induces Broad Protection against Oncogenic and Mucosal Human Papillomaviruses
    Somayeh Pouyanfard, Gloria Spagnoli, Lorenzo Bulli, Kathrin Balz, Fan Yang, Caroline Odenwald, Hanna Seitz, Filipe C. Mariz, Angelo Bolchi, Simone Ottonello, Martin Müller
  • Virus-Cell Interactions | Spotlight
    Interferon Gamma Prevents Infectious Entry of Human Papillomavirus 16 via an L2-Dependent Mechanism
    Patricia M. Day, Cynthia D. Thompson, Douglas R. Lowy, John T. Schiller
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