inverted repeat regions

  • Marek’s Disease Virus Requires Both Copies of the Inverted Repeat Regions for Efficient <em>In Vivo</em> Replication and Pathogenesis
    Pathogenesis and Immunity
    Marek’s Disease Virus Requires Both Copies of the Inverted Repeat Regions for Efficient In Vivo Replication and Pathogenesis

    Marek’s disease virus (MDV) is a highly oncogenic alphaherpesvirus that infects chickens and causes losses in the poultry industry of up to $2 billion per year. The virus is also widely used as a model to study alphaherpesvirus pathogenesis and virus-induced tumor development in a natural host. MDV and most other herpesviruses harbor direct or inverted repeats regions in their genome. However, the role of these sequence duplications in...

    Tereza Vychodil, Andelé M. Conradie, Jakob Trimpert, Amr Aswad, Luca D. Bertzbach, Benedikt B. Kaufer
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