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immune correlates

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    Revisiting the Correlate of Reduced HIV Infection Risk in the Rv144 Vaccine Trial
    Commentary
    Revisiting the Correlate of Reduced HIV Infection Risk in the Rv144 Vaccine Trial

    The RV144 vaccine trial is the only clinical study to have shown a modest but statistically significant decrease in HIV infection risk. RV144 and the subsequent studies identifying the level of V1V2-specific antibodies as a correlate of reduced infection risk are still controversial despite many papers supporting and expanding the initial study.

    Susan Zolla-Pazner, Peter B. Gilbert
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