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HLA-B Antigens

  • Cellular Response to Infection
    Accumulation of Pol Mutations Selected by HLA-B*52:01-C*12:02 Protective Haplotype-Restricted Cytotoxic T Lymphocytes Causes Low Plasma Viral Load Due to Low Viral Fitness of Mutant Viruses
    Hayato Murakoshi, Madoka Koyanagi, Takayuki Chikata, Mohammad Arif Rahman, Nozomi Kuse, Keiko Sakai, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi
  • Pathogenesis and Immunity
    Early Selection in Gag by Protective HLA Alleles Contributes to Reduced HIV-1 Replication Capacity That May Be Largely Compensated for in Chronic Infection
    Mark A. Brockman, Zabrina L. Brumme, Chanson J. Brumme, Toshiyuki Miura, Jennifer Sela, Pamela C. Rosato, Carl M. Kadie, Jonathan M. Carlson, Tristan J. Markle, Hendrik Streeck, Anthony D. Kelleher, Martin Markowitz, Heiko Jessen, Eric Rosenberg, Marcus Altfeld, P. Richard Harrigan, David Heckerman, Bruce D. Walker, Todd M. Allen
  • Pathogenesis and Immunity
    Long-Term Control of HIV-1 in Hemophiliacs Carrying Slow-Progressing Allele HLA-B*5101
    Yuka Kawashima, Nozomi Kuse, Hiroyuki Gatanaga, Takuya Naruto, Mamoru Fujiwara, Sachi Dohki, Tomohiro Akahoshi, Katsumi Maenaka, Philip Goulder, Shinichi Oka, Masafumi Takiguchi
  • Genetic Diversity and Evolution
    Clade-Specific Evolution Mediated by HLA-B*57/5801 in Human Immunodeficiency Virus Type 1 Clade A1 p24
    Lyle R. McKinnon, Rupert Capina, Harold Peters, Mark Mendoza, Joshua Kimani, Charles Wachihi, Anthony Kariri, Makobu Kimani, Meika Richmond, Sandy Koesters Kiazyk, Keith R. Fowke, Walter Jaoko, Ma Luo, T. Blake Ball, Francis A. Plummer
  • Pathogenesis and Immunity
    Maternal Transmission of Human Immunodeficiency Virus Escape Mutations Subverts HLA-B57 Immunodominance but Facilitates Viral Control in the Haploidentical Infant
    Arne Schneidewind, Yanhua Tang, Mark A. Brockman, Elizabeth G. Ryland, Jacqueline Dunkley-Thompson, Julianne C. Steel-Duncan, M. Anne St. John, Joseph A. Conrad, Spyros A. Kalams, Francine Noel, Todd M. Allen, Celia D. Christie, Margaret E. Feeney
  • Pathogenesis and Immunity
    Effective Downregulation of HLA-A*2 and HLA-B*57 by Primary Human Immunodeficiency Virus Type 1 Isolates Cultured from Elite Suppressors
    Eric Nou, Yan Zhou, Damaris D. Nou, Joel N. Blankson
  • Pathogenesis and Immunity
    HLA Class I Subtype-Dependent Expansion of KIR3DS1+ and KIR3DL1+ NK Cells during Acute Human Immunodeficiency Virus Type 1 Infection
    Galit Alter, Suzannah Rihn, Katharine Walter, Anne Nolting, Maureen Martin, Eric S. Rosenberg, Jeffrey S. Miller, Mary Carrington, Marcus Altfeld
  • Pathogenesis and Immunity | Spotlight
    HLA-B57/B*5801 Human Immunodeficiency Virus Type 1 Elite Controllers Select for Rare Gag Variants Associated with Reduced Viral Replication Capacity and Strong Cytotoxic T-Lymphotye Recognition
    Toshiyuki Miura, Mark A. Brockman, Arne Schneidewind, Michael Lobritz, Florencia Pereyra, Almas Rathod, Brian L. Block, Zabrina L. Brumme, Chanson J. Brumme, Brett Baker, Alissa C. Rothchild, Bin Li, Alicja Trocha, Emily Cutrell, Nicole Frahm, Christian Brander, Ildiko Toth, Eric J. Arts, Todd M. Allen, Bruce D. Walker
  • Pathogenesis and Immunity
    Reduced Viral Replication Capacity of Human Immunodeficiency Virus Type 1 Subtype C Caused by Cytotoxic-T-Lymphocyte Escape Mutations in HLA-B57 Epitopes of Capsid Protein
    Christian L. Boutwell, Christopher F. Rowley, M. Essex
  • Pathogenesis and Immunity
    Functional Consequences of Human Immunodeficiency Virus Escape from an HLA-B*13-Restricted CD8+ T-Cell Epitope in p1 Gag Protein
    Julia G. Prado, Isobella Honeyborne, Ian Brierley, Maria Carmen Puertas, Javier Martinez-Picado, Philip J. R. Goulder

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