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HIV Integrase

  • Virus-Cell Interactions
    HIV-1 Resistance to Dolutegravir Is Affected by Cellular Histone Acetyltransferase Activity
    Kaitlin Anstett, Bluma Brenner, Thibault Mesplède, Mark A. Wainberg
  • Virus-Cell Interactions
    Allosteric HIV-1 Integrase Inhibitors Lead to Premature Degradation of the Viral RNA Genome and Integrase in Target Cells
    Michaela K. Madison, Dana Q. Lawson, Jennifer Elliott, Ayşe Naz Ozantürk, Pratibha C. Koneru, Dana Townsend, Manel Errando, Mamuka Kvaratskhelia, Sebla B. Kutluay
  • Genome Replication and Regulation of Viral Gene Expression
    Critical Contribution of Tyr15 in the HIV-1 Integrase (IN) in Facilitating IN Assembly and Nonenzymatic Function through the IN Precursor Form with Reverse Transcriptase
    Tatsuro Takahata, Eri Takeda, Minoru Tobiume, Kenzo Tokunaga, Masaru Yokoyama, Yu-Lun Huang, Atsuhiko Hasegawa, Tatsuo Shioda, Hironori Sato, Mari Kannagi, Takao Masuda
  • Vaccines and Antiviral Agents
    Identification of Novel Mutations Responsible for Resistance to MK-2048, a Second-Generation HIV-1 Integrase Inhibitor
    Tamara Bar-Magen, Richard D. Sloan, Daniel A. Donahue, Björn D. Kuhl, Alexandra Zabeida, Hongtao Xu, Maureen Oliveira, Daria J. Hazuda, Mark A. Wainberg
  • Virus-Cell Interactions
    Importin α3 Interacts with HIV-1 Integrase and Contributes to HIV-1 Nuclear Import and Replication
    Zhujun Ao, Kallesh Danappa Jayappa, Binchen Wang, Yingfeng Zheng, Sam Kung, Eric Rassart, Reinhard Depping, Matthias Kohler, Eric A. Cohen, Xiaojian Yao
  • Virus-Cell Interactions
    Role of Human Immunodeficiency Virus Type 1 Integrase in Uncoating of the Viral Core
    Marisa S. Briones, Charles W. Dobard, Samson A. Chow
  • Vaccines and Antiviral Agents
    Selective-Advantage Profile of Human Immunodeficiency Virus Type 1 Integrase Mutants Explains In Vivo Evolution of Raltegravir Resistance Genotypes
    Romina Quercia, Elisabeth Dam, Danielle Perez-Bercoff, François Clavel
  • Virus-Cell Interactions
    Integrase Interacts with Nucleoporin NUP153 To Mediate the Nuclear Import of Human Immunodeficiency Virus Type 1
    Cora L. Woodward, Sarin Prakobwanakit, Sherly Mosessian, Samson A. Chow
  • Vaccines and Antiviral Agents
    Resistance Mutations in Human Immunodeficiency Virus Type 1 Integrase Selected with Elvitegravir Confer Reduced Susceptibility to a Wide Range of Integrase Inhibitors
    Olivia Goethals, Reginald Clayton, Marcia Van Ginderen, Inge Vereycken, Elisabeth Wagemans, Peggy Geluykens, Koen Dockx, Rudy Strijbos, Veerle Smits, Ann Vos, Geert Meersseman, Dirk Jochmans, Kurt Vermeire, Dominique Schols, Sabine Hallenberger, Kurt Hertogs
  • Genetic Diversity and Evolution
    Analysis of Natural Sequence Variation and Covariation in Human Immunodeficiency Virus Type 1 Integrase
    Richard E. Myers, Deenan Pillay

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