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HIV Fusion Inhibitors

  • Vaccines and Antiviral Agents
    Enfuvirtide (T20)-Based Lipopeptide Is a Potent HIV-1 Cell Fusion Inhibitor: Implications for Viral Entry and Inhibition
    Xiaohui Ding, Xiujuan Zhang, Huihui Chong, Yuanmei Zhu, Huamian Wei, Xiyuan Wu, Jinsheng He, Xinquan Wang, Yuxian He
  • Vaccines and Antiviral Agents
    A Lipopeptide HIV-1/2 Fusion Inhibitor with Highly Potent In Vitro, Ex Vivo, and In Vivo Antiviral Activity
    Huihui Chong, Jing Xue, Shengwen Xiong, Zhe Cong, Xiaohui Ding, Yuanmei Zhu, Zixuan Liu, Ting Chen, Yifan Feng, Lei He, Yan Guo, Qiang Wei, Yusen Zhou, Chuan Qin, Yuxian He
  • Vaccines and Antiviral Agents
    Creating an Artificial Tail Anchor as a Novel Strategy To Enhance the Potency of Peptide-Based HIV Fusion Inhibitors
    Shan Su, Yun Zhu, Sheng Ye, Qianqian Qi, Shuai Xia, Zhenxuan Ma, Fei Yu, Qian Wang, Rongguang Zhang, Shibo Jiang, Lu Lu
  • Vaccines and Antiviral Agents
    A Helical Short-Peptide Fusion Inhibitor with Highly Potent Activity against Human Immunodeficiency Virus Type 1 (HIV-1), HIV-2, and Simian Immunodeficiency Virus
    Shengwen Xiong, Pedro Borrego, Xiaohui Ding, Yuanmei Zhu, Andreia Martins, Huihui Chong, Nuno Taveira, Yuxian He
  • Vaccines and Antiviral Agents
    Design of a Potent d-Peptide HIV-1 Entry Inhibitor with a Strong Barrier to Resistance
    Brett D. Welch, J. Nicholas Francis, Joseph S. Redman, Suparna Paul, Matthew T. Weinstock, Jacqueline D. Reeves, Yolanda S. Lie, Frank G. Whitby, Debra M. Eckert, Christopher P. Hill, Michael J. Root, Michael S. Kay
  • Vaccines and Antiviral Agents
    A Maraviroc-Resistant HIV-1 with Narrow Cross-Resistance to Other CCR5 Antagonists Depends on both N-Terminal and Extracellular Loop Domains of Drug-Bound CCR5
    John C. Tilton, Craig B. Wilen, Chukwuka A. Didigu, Rohini Sinha, Jessamina E. Harrison, Caroline Agrawal-Gamse, Elizabeth A. Henning, Frederick D. Bushman, Jeffrey N. Martin, Steven G. Deeks, Robert W. Doms
  • Vaccines and Antiviral Agents | Spotlight
    Identification of a gp41 Core-Binding Molecule with Homologous Sequence of Human TNNI3K-Like Protein as a Novel Human Immunodeficiency Virus Type 1 Entry Inhibitor
    Yun Zhu, Lu Lu, Liling Xu, Hengwen Yang, Shibo Jiang, Ying-Hua Chen
  • Vaccines and Antiviral Agents
    A Low-Molecular-Weight Entry Inhibitor of both CCR5- and CXCR4-Tropic Strains of Human Immunodeficiency Virus Type 1 Targets a Novel Site on gp41
    Edward J. Murray, Daniel P. Leaman, Nishant Pawa, Hannah Perkins, Chris Pickford, Manos Perros, Michael B. Zwick, Scott L. Butler
  • Pathogenesis and Immunity
    The Infectious Molecular Clone and Pseudotyped Virus Models of Human Immunodeficiency Virus Type 1 Exhibit Significant Differences in Virion Composition with Only Moderate Differences in Infectivity and Inhibition Sensitivity
    Nicholas M. Provine, Wendy Blay Puryear, Xueling Wu, Julie Overbaugh, Nancy L. Haigwood
  • Vaccines and Antiviral Agents
    Combinations of the First and Next Generations of Human Immunodeficiency Virus (HIV) Fusion Inhibitors Exhibit a Highly Potent Synergistic Effect against Enfuvirtide- Sensitive and -Resistant HIV Type 1 Strains
    Chungen Pan, Lifeng Cai, Hong Lu, Zhi Qi, Shibo Jiang

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