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hepacivirus

  • Pathogenesis and Immunity | Spotlight
    Hepatitis C Virus-Specific T Cell Receptor mRNA-Engineered Human T Cells: Impact of Antigen Specificity on Functional Properties
    Anangi Balasiddaiah, Haleh Davanian, Soo Aleman, Anna Pasetto, Lars Frelin, Matti Sällberg, Volker Lohmann, Sarene Koh, Antonio Bertoletti, Margaret Chen
  • Structure and Assembly | Spotlight
    Identification of Novel Functions for Hepatitis C Virus Envelope Glycoprotein E1 in Virus Entry and Assembly
    Juliano G. Haddad, Yves Rouillé, Xavier Hanoulle, Véronique Descamps, Monzer Hamze, Fouad Dabboussi, Thomas F. Baumert, Gilles Duverlie, Muriel Lavie, Jean Dubuisson
  • Vaccines and Antiviral Agents
    Computational Prediction of the Heterodimeric and Higher-Order Structure of gpE1/gpE2 Envelope Glycoproteins Encoded by Hepatitis C Virus
    Holly Freedman, Michael R. Logan, Darren Hockman, Julia Koehler Leman, John Lok Man Law, Michael Houghton
  • Structure and Assembly
    Functional Analysis of Hepatitis C Virus (HCV) Envelope Protein E1 Using a trans-Complementation System Reveals a Dual Role of a Putative Fusion Peptide of E1 in both HCV Entry and Morphogenesis
    Yimin Tong, Xiaojing Chi, Wei Yang, Jin Zhong
  • Structure and Assembly
    A Point Mutation in the N-Terminal Amphipathic Helix α0 in NS3 Promotes Hepatitis C Virus Assembly by Altering Core Localization to the Endoplasmic Reticulum and Facilitating Virus Budding
    Yu Yan, Ying He, Bertrand Boson, Xuesong Wang, François-Loïc Cosset, Jin Zhong
  • Genetic Diversity and Evolution
    Characterization of Hepatitis C Virus (HCV) Envelope Diversification from Acute to Chronic Infection within a Sexually Transmitted HCV Cluster by Using Single-Molecule, Real-Time Sequencing
    Cynthia K. Y. Ho, Jayna Raghwani, Sylvie Koekkoek, Richard H. Liang, Jan T. M. Van der Meer, Marc Van Der Valk, Menno De Jong, Oliver G. Pybus, Janke Schinkel, Richard Molenkamp
    and on behalf of the MOSAIC (MSM Observational Study of Acute Infection with Hepatitis C) Study Group
  • Structure and Assembly
    An Optimized Hepatitis C Virus E2 Glycoprotein Core Adopts a Functional Homodimer That Efficiently Blocks Virus Entry
    Kathleen McCaffrey, Irene Boo, Catherine M. Owczarek, Matthew P. Hardy, Matthew A. Perugini, Louis Fabri, Pierre Scotney, Pantelis Poumbourios, Heidi E. Drummer
  • Virus-Cell Interactions
    Mice Expressing Minimally Humanized CD81 and Occludin Genes Support Hepatitis C Virus Uptake In Vivo
    Qiang Ding, Markus von Schaewen, Gabriela Hrebikova, Brigitte Heller, Lisa Sandmann, Mario Plaas, Alexander Ploss
  • Genome Replication and Regulation of Viral Gene Expression
    Amino Acid Mutations in the NS4A Region of Hepatitis C Virus Contribute to Viral Replication and Infectious Virus Production
    Asako Murayama, Nao Sugiyama, Ryosuke Suzuki, Masaki Moriyama, Noriko Nakamura, Hidenori Mochizuki, Takaji Wakita, Takanobu Kato
  • Virus-Cell Interactions
    Hepatitis C Virus-Induced Rab32 Aggregation and Its Implications for Virion Assembly
    Tu M. Pham, Si C. Tran, Yun-Sook Lim, Soon B. Hwang

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