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Genetic Therapy

  • Gene Delivery
    Respiratory Syncytial Virus Engineered To Express the Cystic Fibrosis Transmembrane Conductance Regulator Corrects the Bioelectric Phenotype of Human Cystic Fibrosis Airway Epithelium In Vitro
    Anna R. Kwilas, Mark A. Yednak, Liqun Zhang, Rachael Liesman, Peter L. Collins, Raymond J. Pickles, Mark E. Peeples
  • Pathogenesis and Immunity
    Inhibition of In Vivo HIV Infection in Humanized Mice by Gene Therapy of Human Hematopoietic Stem Cells with a Lentiviral Vector Encoding a Broadly Neutralizing Anti-HIV Antibody
    Aviva Joseph, Jian Hua Zheng, Ken Chen, Monica Dutta, Cindy Chen, Gabriela Stiegler, Renate Kunert, Antonia Follenzi, Harris Goldstein
  • Gene Delivery
    Self-Inactivating Alpharetroviral Vectors with a Split-Packaging Design
    Julia D. Suerth, Tobias Maetzig, Melanie Galla, Christopher Baum, Axel Schambach
  • Gene Delivery
    In Vivo Retargeting of Adenovirus Type 5 to αvβ6 Integrin Results in Reduced Hepatotoxicity and Improved Tumor Uptake following Systemic Delivery
    Lynda Coughlan, Sabari Vallath, Antonio Saha, Magdalena Flak, Iain A. McNeish, Georges Vassaux, John F. Marshall, Ian R. Hart, Gareth J. Thomas
  • Gene Delivery
    Novel Immunocompetent Murine Tumor Model for Evaluation of Conditionally Replication-Competent (Oncolytic) Murine Adenoviral Vectors
    Michael Robinson, Betty Li, Ying Ge, Derek Ko, Satya Yendluri, Thomas Harding, Melinda VanRoey, Katherine R. Spindler, Karin Jooss
  • Gene Delivery
    Robust In Vivo Transduction of a Genetically Stable Epstein-Barr Virus Episome to Hepatocytes in Mice by a Hybrid Viral Vector
    Sean D. Gallaher, Jose S. Gil, Oliver Dorigo, Arnold J. Berk
  • Pathogenesis and Immunity
    Treatment of Chronic Viral Hepatitis in Woodchucks by Prolonged Intrahepatic Expression of Interleukin-12
    Julien Crettaz, Itziar Otano, Laura Ochoa, Alberto Benito, Astrid Paneda, Igor Aurrekoetxea, Pedro Berraondo, Juan Roberto Rodríguez-Madoz, Aurora Astudillo, Florian Kreppel, Stefan Kochanek, Juan Ruiz, Stephan Menne, Jesus Prieto, Gloria Gonzalez-Aseguinolaza
  • Gene Delivery
    Insertional Gene Activation by Lentiviral and Gammaretroviral Vectors
    Marieke Bokhoven, Sam L. Stephen, Sean Knight, Evelien F. Gevers, Iain C. Robinson, Yasuhiro Takeuchi, Mary K. Collins
  • Vaccines and Antiviral Agents
    Lentivirus Vector Can Be Readministered to Nasal Epithelia without Blocking Immune Responses
    Patrick L. Sinn, Ariadna C. Arias, Kim A. Brogden, Paul B. McCray
  • Vaccines and Antiviral Agents
    Reduction in Severity of a Herpes Simplex Virus Type 1 Murine Infection by Treatment with a Ribozyme Targeting the UL20 Gene RNA
    Jia Liu, Alfred S. Lewin, Sonal S. Tuli, Steven C. Ghivizzani, Gregory S. Schultz, David C. Bloom

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