Genetic Therapy

Gene Delivery
Respiratory Syncytial Virus Engineered To Express the Cystic Fibrosis Transmembrane Conductance Regulator Corrects the Bioelectric Phenotype of Human Cystic Fibrosis Airway Epithelium In Vitro
Anna R. Kwilas, Mark A. Yednak, Liqun Zhang, Rachael Liesman, Peter L. Collins, Raymond J. Pickles, Mark E. Peeples
Pathogenesis and Immunity
Inhibition of In Vivo HIV Infection in Humanized Mice by Gene Therapy of Human Hematopoietic Stem Cells with a Lentiviral Vector Encoding a Broadly Neutralizing Anti-HIV Antibody
Aviva Joseph, Jian Hua Zheng, Ken Chen, Monica Dutta, Cindy Chen, Gabriela Stiegler, Renate Kunert, Antonia Follenzi, Harris Goldstein
Gene Delivery
Self-Inactivating Alpharetroviral Vectors with a Split-Packaging Design
Julia D. Suerth, Tobias Maetzig, Melanie Galla, Christopher Baum, Axel Schambach
Gene Delivery
In Vivo Retargeting of Adenovirus Type 5 to αvβ6 Integrin Results in Reduced Hepatotoxicity and Improved Tumor Uptake following Systemic Delivery
Lynda Coughlan, Sabari Vallath, Antonio Saha, Magdalena Flak, Iain A. McNeish, Georges Vassaux, John F. Marshall, Ian R. Hart, Gareth J. Thomas
Gene Delivery
Novel Immunocompetent Murine Tumor Model for Evaluation of Conditionally Replication-Competent (Oncolytic) Murine Adenoviral Vectors
Michael Robinson, Betty Li, Ying Ge, Derek Ko, Satya Yendluri, Thomas Harding, Melinda VanRoey, Katherine R. Spindler, Karin Jooss
Gene Delivery
Robust In Vivo Transduction of a Genetically Stable Epstein-Barr Virus Episome to Hepatocytes in Mice by a Hybrid Viral Vector
Sean D. Gallaher, Jose S. Gil, Oliver Dorigo, Arnold J. Berk
Pathogenesis and Immunity
Treatment of Chronic Viral Hepatitis in Woodchucks by Prolonged Intrahepatic Expression of Interleukin-12
Julien Crettaz, Itziar Otano, Laura Ochoa, Alberto Benito, Astrid Paneda, Igor Aurrekoetxea, Pedro Berraondo, Juan Roberto Rodríguez-Madoz, Aurora Astudillo, Florian Kreppel, Stefan Kochanek, Juan Ruiz, Stephan Menne, Jesus Prieto, Gloria Gonzalez-Aseguinolaza
Gene Delivery
Insertional Gene Activation by Lentiviral and Gammaretroviral Vectors
Marieke Bokhoven, Sam L. Stephen, Sean Knight, Evelien F. Gevers, Iain C. Robinson, Yasuhiro Takeuchi, Mary K. Collins
Vaccines and Antiviral Agents
Lentivirus Vector Can Be Readministered to Nasal Epithelia without Blocking Immune Responses
Patrick L. Sinn, Ariadna C. Arias, Kim A. Brogden, Paul B. McCray
Vaccines and Antiviral Agents
Reduction in Severity of a Herpes Simplex Virus Type 1 Murine Infection by Treatment with a Ribozyme Targeting the U_L20 Gene RNA
Jia Liu, Alfred S. Lewin, Sonal S. Tuli, Steven C. Ghivizzani, Gregory S. Schultz, David C. Bloom

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