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Drug Resistance, Viral

  • Vaccines and Antiviral Agents
    Resistance Mutations in Human Immunodeficiency Virus Type 1 Integrase Selected with Elvitegravir Confer Reduced Susceptibility to a Wide Range of Integrase Inhibitors
    Olivia Goethals, Reginald Clayton, Marcia Van Ginderen, Inge Vereycken, Elisabeth Wagemans, Peggy Geluykens, Koen Dockx, Rudy Strijbos, Veerle Smits, Ann Vos, Geert Meersseman, Dirk Jochmans, Kurt Vermeire, Dominique Schols, Sabine Hallenberger, Kurt Hertogs
  • Pathogenesis and Immunity
    Oseltamivir-Resistant Influenza A Viruses Are Transmitted Efficiently among Guinea Pigs by Direct Contact but Not by Aerosol
    Nicole M. Bouvier, Anice C. Lowen, Peter Palese
  • Genetic Diversity and Evolution
    Analysis of Natural Sequence Variation and Covariation in Human Immunodeficiency Virus Type 1 Integrase
    Richard E. Myers, Deenan Pillay
  • Vaccines and Antiviral Agents | Spotlight
    In Vivo Emergence of Vicriviroc Resistance in a Human Immunodeficiency Virus Type 1 Subtype C-Infected Subject
    Athe M. N. Tsibris, Manish Sagar, Roy M. Gulick, Zhaohui Su, Michael Hughes, Wayne Greaves, Mani Subramanian, Charles Flexner, Françoise Giguel, Kay E. Leopold, Eoin Coakley, Daniel R. Kuritzkes
  • Vaccines and Antiviral Agents
    Selection of T1249-Resistant Human Immunodeficiency Virus Type 1 Variants
    Dirk Eggink, Christopher E. Baldwin, Yiqun Deng, Johannes P. M. Langedijk, Min Lu, Rogier W. Sanders, Ben Berkhout
  • Vaccines and Antiviral Agents
    Ninety-Nine Is Not Enough: Molecular Characterization of Inhibitor-Resistant Human Immunodeficiency Virus Type 1 Protease Mutants with Insertions in the Flap Region
    Milan Kožíšek, Klára Grantz Šašková, Pavlína Řezáčová, Jiří Brynda, Noortje M. van Maarseveen, Dorien De Jong, Charles A. Boucher, Ron M. Kagan, Monique Nijhuis, Jan Konvalinka
  • Vaccines and Antiviral Agents
    Persistence of Transmitted Drug Resistance among Subjects with Primary Human Immunodeficiency Virus Infection
    Susan J. Little, Simon D. W. Frost, Joseph K. Wong, Davey M. Smith, Sergei L. Kosakovsky Pond, Caroline C. Ignacio, Neil T. Parkin, Christos J. Petropoulos, Douglas D. Richman
  • Genome Replication and Regulation of Viral Gene Expression
    Cyclophilin A Is an Essential Cofactor for Hepatitis C Virus Infection and the Principal Mediator of Cyclosporine Resistance In Vitro
    Feng Yang, Jason M. Robotham, Heather B. Nelson, Andre Irsigler, Rachael Kenworthy, Hengli Tang
  • Vaccines and Antiviral Agents
    Amino Acid Mutation N348I in the Connection Subdomain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Confers Multiclass Resistance to Nucleoside and Nonnucleoside Reverse Transcriptase Inhibitors
    Atsuko Hachiya, Eiichi N. Kodama, Stefan G. Sarafianos, Matthew M. Schuckmann, Yasuko Sakagami, Masao Matsuoka, Masafumi Takiguchi, Hiroyuki Gatanaga, Shinichi Oka
  • Vaccines and Antiviral Agents
    Broad Antiretroviral Activity and Resistance Profile of the Novel Human Immunodeficiency Virus Integrase Inhibitor Elvitegravir (JTK-303/GS-9137)
    Kazuya Shimura, Eiichi Kodama, Yasuko Sakagami, Yuji Matsuzaki, Wataru Watanabe, Kazunobu Yamataka, Yasuo Watanabe, Yoshitsugu Ohata, Satoki Doi, Motohide Sato, Mitsuki Kano, Satoru Ikeda, Masao Matsuoka

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