Drug Resistance, Viral

Vaccines and Antiviral Agents
Actinomycin D Induces High-Level Resistance to Thymidine Analogs in Replication of Human Immunodeficiency Virus Type 1 by Interfering with Host Cell Thymidine Kinase Expression
Tomozumi Imamichi, Michael A. Murphy, Joseph W. Adelsberger, Jun Yang, Catherine M. Watkins, Steve C. Berg, Michael W. Baseler, Richard A. Lempicki, Jianhui Guo, Judith G. Levin, H. Clifford Lane
REPLICATION
Isolation and Molecular Characterization of a Nelfinavir (NFV)-Resistant Human Immunodeficiency Virus Type 1 That Exhibits NFV-Dependent Enhancement of Replication
Saori Matsuoka-Aizawa, Hironori Sato, Atsuko Hachiya, Kiyoto Tsuchiya, Yutaka Takebe, Hiroyuki Gatanaga, Satoshi Kimura, Shinichi Oka
Vaccines and Antiviral Agents
Crystal Structures of Zidovudine- or Lamivudine-Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptases Containing Mutations at Codons 41, 184, and 215
P. P. Chamberlain, J. Ren, C. E. Nichols, L. Douglas, J. Lennerstrand, B. A. Larder, D. I. Stuart, D. K. Stammers
REPLICATION
Nucleoside Analog Resistance Caused by Insertions in the Fingers of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Involves ATP-Mediated Excision
Paul L. Boyer, Stefan G. Sarafianos, Edward Arnold, Stephen H. Hughes
Vaccines and Antiviral Agents
Combination of Drugs and Drug-Resistant Reverse Transcriptase Results in a Multiplicative Increase of Human Immunodeficiency Virus Type 1 Mutant Frequencies
Louis M. Mansky, Dennis K. Pearl, Lisa C. Gajary
Vaccines and Antiviral Agents
Changes in Human Immunodeficiency Virus Type 1 Gag at Positions L449 and P453 Are Linked to I50V Protease Mutants In Vivo and Cause Reduction of Sensitivity to Amprenavir and Improved Viral Fitness In Vitro
Michael F. Maguire, Rosario Guinea, Philip Griffin, Sarah Macmanus, Robert C. Elston, Josie Wolfram, Naomi Richards, Mary H. Hanlon, David J. T. Porter, Terri Wrin, Neil Parkin, Margaret Tisdale, Eric Furfine, Chris Petropoulos, B. Wendy Snowden, Jörg-Peter Kleim
Vaccines and Antiviral Agents
A Mutation in the 3′ Region of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase (Y318F) Associated with Nonnucleoside Reverse Transcriptase Inhibitor Resistance
P. Richard Harrigan, Mahboob Salim, David K. Stammers, Brian Wynhoven, Zabrina L. Brumme, Paula McKenna, Brendan Larder, S. D. Kemp
Vaccines and Antiviral Agents
Mutations of the Woodchuck Hepatitis Virus Polymerase Gene That Confer Resistance to Lamivudine and 2′-Fluoro-5-Methyl-β-l-Arabinofuranosyluracil
Toshiki Yamamoto, Samuel Litwin, Tianlun Zhou, Yuao Zhu, Lynn Condreay, Phillip Furman, William S. Mason
Vaccines and Antiviral Agents
Altered Substrate Specificity of Drug-Resistant Human Immunodeficiency Virus Type 1 Protease
Deborah S. Dauber, Rainer Ziermann, Neil Parkin, Dustin J. Maly, Sami Mahrus, Jennifer L. Harris, Jon A. Ellman, Christos Petropoulos, Charles S. Craik

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Drug Resistance, Viral

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