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drug design

  • Vaccines and Antiviral Agents
    Dengue Virus NS2B/NS3 Protease Inhibitors Exploiting the Prime Side
    Kuan-Hung Lin, Akbar Ali, Linah Rusere, Djade I. Soumana, Nese Kurt Yilmaz, Celia A. Schiffer
  • Vaccines and Antiviral Agents
    Design and In Vivo Characterization of Immunoconjugates Targeting HIV gp160
    Seth H. Pincus, Kejing Song, Grace A. Maresh, Anderson Frank, David Worthylake, Hye-Kyung Chung, Patricia Polacino, Dean H. Hamer, Cody P. Coyne, Michael G. Rosenblum, John W. Marks, Gang Chen, Deborah Weiss, Victor Ghetie, Ellen S. Vitetta, James E. Robinson, Shiu-Lok Hu
  • Vaccines and Antiviral Agents
    Creating an Artificial Tail Anchor as a Novel Strategy To Enhance the Potency of Peptide-Based HIV Fusion Inhibitors
    Shan Su, Yun Zhu, Sheng Ye, Qianqian Qi, Shuai Xia, Zhenxuan Ma, Fei Yu, Qian Wang, Rongguang Zhang, Shibo Jiang, Lu Lu
  • Vaccines and Antiviral Agents
    Design of a Potent d-Peptide HIV-1 Entry Inhibitor with a Strong Barrier to Resistance
    Brett D. Welch, J. Nicholas Francis, Joseph S. Redman, Suparna Paul, Matthew T. Weinstock, Jacqueline D. Reeves, Yolanda S. Lie, Frank G. Whitby, Debra M. Eckert, Christopher P. Hill, Michael J. Root, Michael S. Kay
  • Structure and Assembly | Spotlight
    Structures of Two Coronavirus Main Proteases: Implications for Substrate Binding and Antiviral Drug Design
    Xiaoyu Xue, Hongwei Yu, Haitao Yang, Fei Xue, Zhixin Wu, Wei Shen, Jun Li, Zhe Zhou, Yi Ding, Qi Zhao, Xuejun C. Zhang, Ming Liao, Mark Bartlam, Zihe Rao
  • Vaccines and Antiviral Agents
    Rational Design of Genetically Stable, Live-Attenuated Poliovirus Vaccines of All Three Serotypes: Relevance to Poliomyelitis Eradication
    Andrew J. Macadam, Geraldine Ferguson, David M. Stone, Janet Meredith, Sarah Knowlson, Ghazi Auda, Jeffrey W. Almond, Philip D. Minor
  • Structure and Assembly
    Altered Gag Polyprotein Cleavage Specificity of Feline Immunodeficiency Virus/Human Immunodeficiency Virus Mutant Proteases as Demonstrated in a Cell-Based Expression System
    Ying-Chuan Lin, Ashraf Brik, Aymeric de Parseval, Karen Tam, Bruce E. Torbett, Chi-Huey Wong, John H. Elder
  • Vaccines and Antiviral Agents | Spotlight
    Combinatorial Approach to Hepadnavirus-Like Particle Vaccine Design
    Jean-Noel Billaud, Darrell Peterson, Margaret Barr, Antony Chen, Matti Sallberg, Fermin Garduno, Phillip Goldstein, Wendy McDowell, Janice Hughes, Joyce Jones, David Milich
  • Vaccines and Antiviral Agents
    Inhibitors of Respiratory Syncytial Virus Replication Target Cotranscriptional mRNA Guanylylation by Viral RNA-Dependent RNA Polymerase
    Michel Liuzzi, Stephen W. Mason, Mireille Cartier, Carol Lawetz, Robert S. McCollum, Nathalie Dansereau, Gordon Bolger, Nicole Lapeyre, Yvon Gaudette, Lisette Lagacé, Marie-Josée Massariol, Florence Dô, Paul Whitehead, Lyne Lamarre, Erika Scouten, Josée Bordeleau, Serge Landry, Jean Rancourt, Gulrez Fazal, Bruno Simoneau
  • Vaccines and Antiviral Agents
    Universal Influenza B Vaccine Based on the Maturational Cleavage Site of the Hemagglutinin Precursor
    Elisabetta Bianchi, Xiaoping Liang, Paolo Ingallinella, Marco Finotto, Michael A. Chastain, Jiang Fan, Tong-Ming Fu, Hong Chang Song, Melanie S. Horton, Daniel C. Freed, Walter Manger, Emily Wen, Li Shi, Roxana Ionescu, Colleen Price, Marc Wenger, Emilio A. Emini, Riccardo Cortese, Gennaro Ciliberto, John W. Shiver, Antonello Pessi

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