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cytoplasm

  • Cytoplasmic Parvovirus Capsids Recruit Importin Beta for Nuclear Delivery
    Virus-Cell Interactions
    Cytoplasmic Parvovirus Capsids Recruit Importin Beta for Nuclear Delivery

    Parvoviruses are small DNA viruses that deliver their DNA into the postmitotic nuclei, which is an important step for parvoviral gene and cancer therapies. Limitations in virus-receptor interactions or endocytic entry do not fully explain the low transduction/infection efficiency, indicating a bottleneck after virus entry into the cytoplasm. We thus investigated the transfer of parvovirus capsids from the cytoplasm to the nucleus,...

    Elina Mäntylä, Vesa Aho, Michael Kann, Maija Vihinen-Ranta
  • Genome Replication and Regulation of Viral Gene Expression
    Full-Length Isoforms of Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Accumulate in the Cytoplasm of Cells Undergoing the Lytic Cycle of Replication
    H. Jacques Garrigues, Kellie Howard, Serge Barcy, Minako Ikoma, Ashlee V. Moses, Gail H. Deutsch, David Wu, Keiji Ueda, Timothy M. Rose
  • Transformation and Oncogenesis
    Human Papillomavirus 16 (HPV-16), HPV-18, and HPV-31 E6 Override the Normal Phosphoregulation of E6AP Enzymatic Activity
    Jayashree Thatte, Lawrence Banks
  • Virus-Cell Interactions
    Herpes Simplex Virus gE/gI and US9 Promote both Envelopment and Sorting of Virus Particles in the Cytoplasm of Neurons, Two Processes That Precede Anterograde Transport in Axons
    Grayson DuRaine, Todd W. Wisner, Paul Howard, Melissa Williams, David C. Johnson
  • Structure and Assembly
    Cytoplasmic Motifs in the Nipah Virus Fusion Protein Modulate Virus Particle Assembly and Egress
    Gunner P. Johnston, Erik M. Contreras, Jeffrey Dabundo, Bryce A. Henderson, Keesha M. Matz, Victoria Ortega, Alfredo Ramirez, Arnold Park, Hector C. Aguilar
  • Virus-Cell Interactions
    Subcellular Localization of HIV-1 gag-pol mRNAs Regulates Sites of Virion Assembly
    Jordan T. Becker, Nathan M. Sherer
  • Structure and Assembly
    Potent Inhibition of Human Cytomegalovirus by Modulation of Cellular SNARE Syntaxin 5
    Linda Cruz, Nicholas T. Streck, Kevin Ferguson, Trisha Desai, Dhimant H. Desai, Shantu G. Amin, Nicholas J. Buchkovich
  • Erratum
    Identification of the Cellular Prohibitin 1/Prohibitin 2 Heterodimer as an Interaction Partner of the C-Terminal Cytoplasmic Domain of the HIV-1 Glycoprotein
    Vanessa Emerson, Denise Holtkotte, Tanya Pfeiffer, I-Hsuan Wang, Martina Schnölzer, Tore Kempf, Valerie Bosch
  • Cellular Response to Infection
    Activation of the Interferon Response by Human Cytomegalovirus Occurs via Cytoplasmic Double-Stranded DNA but Not Glycoprotein B
    Victor R. DeFilippis, Tina Sali, David Alvarado, Laura White, Wade Bresnahan, Klaus J. Früh
  • Genome Replication and Regulation of Viral Gene Expression
    Nucleocytoplasmic Shuttling of Human Cytomegalovirus UL84 Is Essential for Virus Growth
    Yang Gao, Dominique Kagele, Kate Smallenberg, Gregory S. Pari

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