CD4-Positive T-Lymphocytes

Virus-Cell Interactions | Spotlight
T Cell-Macrophage Fusion Triggers Multinucleated Giant Cell Formation for HIV-1 Spreading
Lucie Bracq, Maorong Xie, Marie Lambelé, Lan-Trang Vu, Julie Matz, Alain Schmitt, Jérôme Delon, Paul Zhou, Clotilde Randriamampita, Jérôme Bouchet, Serge Benichou
Pathogenesis and Immunity
Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection
Jeffrey E. Teigler, Gennadiy Zelinskyy, Michael A. Eller, Diane L. Bolton, Mary Marovich, Alexander D. Gordon, Aljawharah Alrubayyi, Galit Alter, Merlin L. Robb, Jeffrey N. Martin, Steven G. Deeks, Nelson L. Michael, Ulf Dittmer, Hendrik Streeck
Pathogenesis and Immunity
Human Cytomegalovirus Particles Treated with Specific Antibodies Induce Intrinsic and Adaptive but Not Innate Immune Responses
Zeguang Wu, Ruifang Qin, Li Wang, Matteo Bosso, Myriam Scherer, Thomas Stamminger, Dominik Hotter, Thomas Mertens, Giada Frascaroli
Virus-Cell Interactions
Extracellular Matrix Proteins Mediate HIV-1 gp120 Interactions with α₄β₇
David Plotnik, Wenjin Guo, Brad Cleveland, Priska von Haller, Jimmy K. Eng, Miklos Guttman, Kelly K. Lee, James Arthos, Shiu-Lok Hu
Pathogenesis and Immunity
Critical Role for Monocytes/Macrophages in Rapid Progression to AIDS in Pediatric Simian Immunodeficiency Virus-Infected Rhesus Macaques
Chie Sugimoto, Kristen M. Merino, Atsuhiko Hasegawa, Xiaolei Wang, Xavier A. Alvarez, Hiroshi Wakao, Kazuyasu Mori, Woong-Ki Kim, Ronald S. Veazey, Elizabeth S. Didier, Marcelo J. Kuroda
Pathogenesis and Immunity
Epigenetic Metabolite Acetate Inhibits Class I/II Histone Deacetylases, Promotes Histone Acetylation, and Increases HIV-1 Integration in CD4⁺ T Cells
Jean-François Bolduc, Laurent Hany, Corinne Barat, Michel Ouellet, Michel J. Tremblay
Vaccines and Antiviral Agents
Broadening CD4⁺ and CD8⁺ T Cell Responses against Hepatitis C Virus by Vaccination with NS3 Overlapping Peptide Panels in Cross-Priming Liposomes
Jonathan Filskov, Marianne Mikkelsen, Paul R. Hansen, Jan P. Christensen, Allan R. Thomsen, Peter Andersen, Jens Bukh, Else Marie Agger
Pathogenesis and Immunity
Simian Immunodeficiency Virus Targeting of CXCR3⁺ CD4⁺ T Cells in Secondary Lymphoid Organs Is Associated with Robust CXCL10 Expression in Monocyte/Macrophage Subsets
Masayuki Fujino, Hirotaka Sato, Tomotaka Okamura, Akihiko Uda, Satoshi Takeda, Nursarat Ahmed, Shigeyuki Shichino, Teiichiro Shiino, Yohei Saito, Satoru Watanabe, Chie Sugimoto, Marcelo J. Kuroda, Manabu Ato, Yoshiyuki Nagai, Shuji Izumo, Kouji Matsushima, Masaaki Miyazawa, Aftab A. Ansari, Francois Villinger, Kazuyasu Mori
Pathogenesis and Immunity
Maintenance of the HIV Reservoir Is Antagonized by Selective BCL2 Inhibition
Nathan W. Cummins, Amy M. Sainski-Nguyen, Sekar Natesampillai, Fatma Aboulnasr, Scott Kaufmann, Andrew D. Badley
Vaccines and Antiviral Agents
Superiority in Rhesus Macaques of Targeting HIV-1 Env gp140 to CD40 versus LOX-1 in Combination with Replication-Competent NYVAC-KC for Induction of Env-Specific Antibody and T Cell Responses
Gerard Zurawski, Xiaoying Shen, Sandra Zurawski, Georgia D. Tomaras, David C. Montefiori, Mario Roederer, Guido Ferrari, Christine Lacabaratz, Peter Klucar, Zhiqing Wang, Kathryn E. Foulds, Shing-Fen Kao, Xuesong Yu, Alicia Sato, Nicole L. Yates, Celia LaBranche, Sherry Stanfield-Oakley, Karen Kibler, Bertram Jacobs, Andres Salazar, Steve Self, William Fulp, Raphael Gottardo, Lindsey Galmin, Deborah Weiss, Anthony Cristillo, Giuseppe Pantaleo, Yves Levy

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CD4-Positive T-Lymphocytes

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