antigenic evolution

  • The Molecular Basis for Antigenic Drift of Human A/H2N2 Influenza Viruses
    Genetic Diversity and Evolution
    The Molecular Basis for Antigenic Drift of Human A/H2N2 Influenza Viruses

    While influenza A viruses of subtype H2N2 were at the origin of the Asian influenza pandemic, little is known about the antigenic changes that occurred during the twelve years of circulation in humans, the role of preexisting immunity, and the evolutionary rates of the virus. In this study, the antigenic map derived from hemagglutination inhibition (HI) titers of cell-cultured virus isolates and ferret postinfection sera displayed a...

    M. Linster, E. J. A. Schrauwen, S. van der Vliet, D. F. Burke, P. Lexmond, T. M. Bestebroer, D. J. Smith, S. Herfst, B. F. Koel, R. A. M. Fouchier
  • Genetic Diversity and Evolution | Spotlight
    Dynamics of Evolution of Poliovirus Neutralizing Antigenic Sites and Other Capsid Functional Domains during a Large and Prolonged Outbreak
    Jing Shaw, Jaume Jorba, Kun Zhao, Jane Iber, Qi Chen, Festus Adu, Adekunle Adeniji, David Bukbuk, Marycelin Baba, Elizabeth Henderson, Naomi Dybdahl-Sissoko, Sharla McDonald, William C. Weldon, Nicksy Gumede, M. Steven Oberste, Olen M. Kew, Cara C. Burns
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