AIDS Vaccines

Open Access

Vaccines and Antiviral Agents
HIV-1 gp120 and Modified Vaccinia Virus Ankara (MVA) gp140 Boost Immunogens Increase Immunogenicity of a DNA/MVA HIV-1 Vaccine
Xiaoying Shen, Rahul Basu, Sheetal Sawant, David Beaumont, Sue Fen Kwa, Celia LaBranche, Kelly E. Seaton, Nicole L. Yates, David C. Montefiori, Guido Ferrari, Linda S. Wyatt, Bernard Moss, S. Munir Alam, Barton F. Haynes, Georgia D. Tomaras, Harriet L. Robinson
Vaccines and Antiviral Agents
High-Throughput Protein Engineering Improves the Antigenicity and Stability of Soluble HIV-1 Envelope Glycoprotein SOSIP Trimers
Jonathan T. Sullivan, Chidananda Sulli, Alberto Nilo, Anila Yasmeen, Gabriel Ozorowski, Rogier W. Sanders, Andrew B. Ward, P. J. Klasse, John P. Moore, Benjamin J. Doranz
Vaccines and Antiviral Agents
HIV DNA-Adenovirus Multiclade Envelope Vaccine Induces gp41 Antibody Immunodominance in Rhesus Macaques
Qifeng Han, Wilton B. Williams, Kevin O. Saunders, Kelly E. Seaton, Kevin J. Wiehe, Nathan Vandergrift, Tarra A. Von Holle, Ashley M. Trama, Robert J. Parks, Kan Luo, Thaddeus C. Gurley, Thomas B. Kepler, Dawn J. Marshall, David C. Montefiori, Laura L. Sutherland, Munir S. Alam, John F. Whitesides, Cindy M. Bowman, Sallie R. Permar, Barney S. Graham, John R. Mascola, Patrick C. Seed, Koen K. A. Van Rompay, Georgia D. Tomaras, M. Anthony Moody, Barton F. Haynes
Vaccines and Antiviral Agents
Monoclonal Antibodies, Derived from Humans Vaccinated with the RV144 HIV Vaccine Containing the HVEM Binding Domain of Herpes Simplex Virus (HSV) Glycoprotein D, Neutralize HSV Infection, Mediate Antibody-Dependent Cellular Cytotoxicity, and Protect Mice from Ocular Challenge with HSV-1
Kening Wang, Georgia D. Tomaras, Sinthujan Jegaskanda, M. Anthony Moody, Hua-Xin Liao, Kyle N. Goodman, Phillip W. Berman, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Sorachai Nitayapan, Jaranit Kaewkungwal, Barton F. Haynes, Jeffrey I. Cohen
Open Access

Vaccines and Antiviral Agents
Cross-Linking of a CD4-Mimetic Miniprotein with HIV-1 Env gp140 Alters Kinetics and Specificities of Antibody Responses against HIV-1 Env in Macaques
Xiaoying Shen, Willy M. Bogers, Nicole L. Yates, Guido Ferrari, Antu K. Dey, William T. Williams, Frederick H. Jaeger, Kevin Wiehe, Sheetal Sawant, S. Munir Alam, Celia C. LaBranche, David C. Montefiori, Loic Martin, Indresh Srivastava, Jonathan Heeney, Susan W. Barnett, Georgia D. Tomaras
Vaccines and Antiviral Agents
Preferential Targeting of Conserved Gag Regions after Vaccination with a Heterologous DNA Prime-Modified Vaccinia Virus Ankara Boost HIV-1 Vaccine Regimen
Asli Bauer, Lilli Podola, Philipp Mann, Marco Missanga, Antelmo Haule, Lwitiho Sudi, Charlotta Nilsson, Bahati Kaluwa, Cornelia Lueer, Maria Mwakatima, Patricia J. Munseri, Leonard Maboko, Merlin L. Robb, Sodsai Tovanabutra, Gustavo Kijak, Mary Marovich, Sheena McCormack, Sarah Joseph, Eligius Lyamuya, Britta Wahren, Eric Sandström, Gunnel Biberfeld, Michael Hoelscher, Muhammad Bakari, Arne Kroidl, Christof Geldmacher
Free

Commentary
Protection against HIV Acquisition in the RV144 Trial
Ronald C. Desrosiers
Pathogenesis and Immunity
Covalent Linkage of HIV-1 Trimers to Synthetic Liposomes Elicits Improved B Cell and Antibody Responses
Shridhar Bale, Geraldine Goebrecht, Armando Stano, Richard Wilson, Takayuki Ota, Karen Tran, Jidnyasa Ingale, Michael B. Zwick, Richard T. Wyatt
Vaccines and Antiviral Agents
Superiority in Rhesus Macaques of Targeting HIV-1 Env gp140 to CD40 versus LOX-1 in Combination with Replication-Competent NYVAC-KC for Induction of Env-Specific Antibody and T Cell Responses
Gerard Zurawski, Xiaoying Shen, Sandra Zurawski, Georgia D. Tomaras, David C. Montefiori, Mario Roederer, Guido Ferrari, Christine Lacabaratz, Peter Klucar, Zhiqing Wang, Kathryn E. Foulds, Shing-Fen Kao, Xuesong Yu, Alicia Sato, Nicole L. Yates, Celia LaBranche, Sherry Stanfield-Oakley, Karen Kibler, Bertram Jacobs, Andres Salazar, Steve Self, William Fulp, Raphael Gottardo, Lindsey Galmin, Deborah Weiss, Anthony Cristillo, Giuseppe Pantaleo, Yves Levy
Vaccines and Antiviral Agents
HIV/AIDS Vaccine Candidates Based on Replication-Competent Recombinant Poxvirus NYVAC-C-KC Expressing Trimeric gp140 and Gag-Derived Virus-Like Particles or Lacking the Viral Molecule B19 That Inhibits Type I Interferon Activate Relevant HIV-1-Specific B and T Cell Immune Functions in Nonhuman Primates
Juan García-Arriaza, Beatriz Perdiguero, Jonathan L. Heeney, Michael S. Seaman, David C. Montefiori, Nicole L. Yates, Georgia D. Tomaras, Guido Ferrari, Kathryn E. Foulds, Mario Roederer, Steven G. Self, Bhavesh Borate, Raphael Gottardo, Sanjay Phogat, Jim Tartaglia, Susan W. Barnett, Brian Burke, Anthony D. Cristillo, Deborah E. Weiss, Carter Lee, Karen V. Kibler, Bertram L. Jacobs, Ralf Wagner, Song Ding, Giuseppe Pantaleo, Mariano Esteban

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AIDS Vaccines

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