TABLE 3

Multivariate analysis of HIV-1 monocyte apoptosisa

Apoptosis typeStatisticCoefficientEstimateSE95% CIt valueP value
ConstitutiveIntercept6.4452812.21194711.8695 to 11.02102.9147.82E−03
IFI270.0037230.00086590.001932 to 0.0055144.2992.67E−04
IFITM2−1.247970.6839378−2.6628 to 0.16686−1.8250.081066
Rb10.3935770.3363558−0.3022 to 1.08941.172.54E−01
Bcl21.8118560.41722570.9488 to 2.67504.3432.40E−04
    Multiple R20.6578
    Adjusted R20.5983
    F statistic11.05 on 4 and 23 DF
    P value3.77E-05
InducedIntercept−98.35421.986−143.9495 to −52.7577−4.4731.90E−04
Log viral load19.8903.53212.5647 to 27.21535.6311.16E−05
IFITM2−5.8994.277−14.7694 to 2.9718−1.3790.18173
Rb115.0375.3323.978022 to 26.09570652.8200.00997
Bax−16.5298.200−33.534222 to 0.4762045−2.0160.0562
    Multiple R20.6612
    Adjusted R20.5996
    F statistic10.73 on 4 and 22 DF
    P value5.59E-05
  • a SE, standard error; CI, confidence interval; DF, degrees of freedom.