TABLE 2

Binding kinetics and affinity for representative H1/H5 cross-reactive antibodies

AntibodyVH segmentKD (M)kon (1/s · M)koff (1/s)
310-18A31-691.70 × 10−91.04 × 1051.76 × 10−5
310-18D51-36.70 × 10−91.04 × 1057.04 × 10−5
310-18F34-342.05 × 10−87.30 × 1041.49 × 10−4
310-18F53-138.00 × 10−92.41 × 1051.93 × 10−4