TABLE 1

Opioid receptor agonist loperamide attenuates rotavirus diarrhea

Infant mouse type (n)No. of mice suffering diarrhea at:
40 h p.i.44 h p.i.48 h p.i.64 h p.i.68 h p.i.
EDIM infected, untreated (13)12/1312/1312/1312/1312/13
EDIM infected, loperamide treated (9)8/90/80/86/82/8
Noninfected, loperamide treated (6)0/60/60/60/60/6
Noninfected, untreated (2)0/20/20/20/20/2