TABLE 2

Summary of PCR-sequenced EEHV3, EEHV4, EEHV5A, EEHV5B, and EEHV6 gene coding regions

Gene/ORF no./IDaHCMV ORFHSV ORFOrientationbProtein nameStatuscPresence/absence of the indicated ORFd
EEHV3 NAP27EEHV4 NAP22EEHV5A NAP28EEHV5A NAP50EEHV5B NAP58EEHV6 NAP35
U39UL55UL29FgBCore+++++
U38UL54UL30FPOLCore++++++
U33UL49NilFCys-richβ/γ++++
U28UL45UL39FRRACore++++
U27.5/ORF-HNilUL40FRRBα/β2++++
U27/ORF-IUL44UL42FPPFCore+++
U45.7/ORF-JNilNilFNovel+
U46UL73UL49AFgNCore+
U47/ORF-DUL74NilRgOβ+
U48UL75UL22RgHCore++++
U48.5/ORF-ENilUL23RTKα/γ++++
U49UL76UL24FCore++++
U50UL77UL25FPAC2Core+++
U51UL78NilFvGPCR1β++++
U57UL86UL19RMCPCore++++
U60ex3UL89UL15ex2RTERex3Core+++++
U62UL91NilFβ/γ+++
U63UL92NilFβ/γ+
U66ex2NilNilRTERex2Core+
U66ex1UL89ex1UL15ex1RTERex1Core+
U70UL98UL12FEXOCore++++++
U71UL99UL11FmyrTeg.Core++++++
U72UL100UL10RgMCore++++++
U73/ORF-GNilUL09FOBPα/β++++++
U76UL104UL06RPORCore++++++
U77UL105UL05FHELCore++++++
U77.5/ORF-MNilNilFNuclearNovel+++
U80.5/ORF-NNilNilRvCXCL1Novel+++
U81UL114UL02RUDGCore+++
U82UL115UL01RgLCore+++
U82.5/ORF-Oex3NilNilRS/TGlyPNovel+++
U82.5/ORF-Oex2NilNilRS/TGlyPNovel+++
U82.5/ORF-Oex1NilNilRS/TGlyPNovel+++
U83.5/ORF-Pex2NilNilRS/TGlyPNovel+
U83.5/ORF-Pex1NilNilRS/TGlyPNovel+
U84.5/ORF-QNilNilRS/TGlyPNovelA
U85.5/ORF-Kex3NilNilRSplGlyPNovel+++
U85.5/ORF-Kex2NilNilRSplGlyPNovel+++
U85.5/ORF-Kex1NilNilRSplGlyPNovel+++
U86.5/ORF-LNilNilRIE-likeNovel+++
  • a ID, identification.

  • b F, forward; R, reverse.

  • c Novel, not found in any other herpesviruses; β, betaherpesvirus subfamily only; Core, common to all herpesvirus subfamilies; β/γ, betaherpesvirus and gammaherpesvirus subfamilies only; α/β, alphaherpesvirus and betaherpesvirus subfamilies only; α/β2, alphaherpesvirus subfamily and roseoloviruses only.

  • d +, partial or intact ORF present (see Table S1 in supplemental material for detailed coordinates, percent divergence, and GenBank accession numbers); A, gene absent.