TABLE 3

Genes with expression levels reversible by IFN-based therapy in patients with chronic HCV infectiona

ProbeGeneGene symbolRatios of gene expression level
Responders at 24 wk of follow-up vs responders at baselineResponders at baseline vs healthy controls
232125_at0.592.56
1557236_atApolipoprotein L, 6APOL60.672.42
227740_atUHM kinase 1UHMK10.682.14
205187_atSMAD family member 5SMAD50.542.09
205091_x_atRecQ protein-like (DNA helicase Q1-like)RECQL0.802.03
212417_atSecretory carrier membrane protein 1SCAMP10.731.96
219844_atChromosome 10 open reading frame 118C10orf1180.651.94
232940_s_atMyeloid/lymphoid or mixed-lineage leukemia 3MLL30.791.90
235003_atUHM kinase 1UHMK10.661.84
210705_s_atTripartite motif-containing 5TRIM50.781.75
213158_at0.851.68
234988_atValosin-containing protein (p97)/p47 complex-interacting protein 1VCPIP10.851.60
1552978_a_atSecretory carrier membrane protein 1SCAMP10.741.60
221510_s_atGlutaminaseGLS0.821.56
1552644_a_atPolyhomeotic homolog 3 (Drosophila)PHC30.861.55
217813_s_atSpindlin 1SPIN10.751.54
202775_s_atSplicing factor, suppressor of white-apricot homolog (Drosophila)SFSWAP1.090.67
213300_atATG2 autophagy-related 2 homolog A (S. cerevisiae)ATG2A1.150.67
201221_s_atSmall nuclear ribonucleoprotein, 70 kDa (U1)SNRNP701.140.66
202032_s_atMannosidase, alpha, class 2A, member 2MAN2A21.300.66
218274_s_atAnkyrin repeat- and zinc finger domain-containing 1ANKZF11.160.65
218376_s_atMicrotubule-associated monooxygenase-, calponin-, and LIM domain-containing 1MICAL11.190.65
232946_s_atNAD synthetase 1NADSYN11.120.65
201244_s_atv-raf-1 murine leukemia viral oncogene homolog 1RAF11.200.64
203249_atEnhancer of zeste homolog 1 (Drosophila)EZH11.190.63
209110_s_atRal guanine nucleotide dissociation stimulator-like 2RGL21.320.62
212708_atMale-specific lethal 1 homolog (Drosophila)MSL11.300.61
230142_s_atCold-inducible RNA binding proteinCIRBP1.230.60
218920_atFamily with sequence similarity 193, member BFAM193B1.250.59
232145_atChromosome 2 open reading frame 68C2orf681.390.59
210113_s_atNLR family, pyrin domain-containing 1NLRP11.320.58
202875_s_atPre-B cell leukemia homeobox 2PBX21.280.56
226340_x_atWAS protein homolog 1, 2, 3, 7 pseudogeneWASH1,2P,3P,7P1.190.55
214780_s_atMyosin IXBMYO9B1.150.55
232543_x_atRho GTPase-activating protein 9ARHGAP91.270.55
227668_atChromosome 17 open reading frame 56C17orf561.300.54
225995_x_atWASP homolog 1,2 pseudogeneWASH1,2P1.140.54
225191_atCold-inducible RNA binding proteinCIRBP1.320.53
1569257_atFormin-like 1FMNL11.590.51
219577_s_atABC1, member 7ABCA71.250.51
202392_s_atPhosphatidylserine decarboxylasePISD1.390.51
210428_s_atHepatocyte growth factor-regulated tyrosine kinase substrateHGS1.160.49
225883_atATG16 autophagy-related 16-like 2 (S. cerevisiae)ATG16L21.540.48
206722_s_atLysophosphatidic acid receptor 2LPAR21.230.48
232077_s_atYippee-like 3 (Drosophila)YPEL31.690.43
  • a UHM, U2AF homology motif; ABC1, ATP binding cassette, subfamily A.