TABLE 1

Subject characteristics

Study subjectStatusaCD4 countb (cells/μl)Viral loadc (RNA copies/ml)HLA class I designation (A1/A2/B1/B2/C1/C2)d
Controllers
    1EC809<50A*03/A*31/B*27/B*57/C*02/C*12
    2EC1,211<50A*02/A*03/B*13/B*18/C*06/C*07
    3EC540<50A*02/A*11/B*35/B*57/C*04/C*06
    4EC603<50A*02/ND/B*13/B*49/C*06/C*07
    5EC643<50A*24/A*31/B*27/B*27/C*02/C*02
    6EC1,389<50A*11/A*31/B*15/B*15/C*03/C*04
    7EC1,916<50A*01/A*24/B*08/B*35/C*04/C*07
    8VC523246A*01/A*26/B*49/B*57/C*06/C*07
    9VC784125A*24/A*25/B*39/B*57/C*06/C*12
    10VC580432A*29/A*32/B*44/B*44/C*05/C*16
    11VC747250A*01/A*03/B*27/B*57/C*02/C*06
    12VC570386A*02/A*03/B*18/B*07/C*07/C*12
    13VC702163A*01/A*02/B*38/B*57/C*06/C*12
    14VC790191A*11/A*26/B*35/B*58/C*04/C*14
    15VC1,181430A*03/A*68/B*13/B*56/C*06/C*07
    Median747125
Progressors
    1TP34922,730A*01/A*01/B*08/B*08/C*07/C*07
    2TP550286,000ND
    3DP44178,400A*01/A*02/B*15/B*57/C*03/C*06
    4TP52239,550A*03/A*24/B*35/B*44/C*02/C*04
    5TP51060,000A*02/A*03/B*07/B*44/C*05/C*07
    6TP175115,240A*24/A*25/B*15/B*58/C*04/C*07
    7TP440622,800A*01/A*01/B*08/B*40/C*03/C*07
    8TP371217,200A*11/A*31/B*08/B*08/C*07/C*07
    9TP4073,455A*02/A*33/B*35/B*44/C*04/C*16
    10TP34023,750ND
    11TP3178,606A*23/A*30/B*08/B*42/C*07/C*17
    12TP448153,286A*01/A*01/B*08/B*08/C*07/C*07
    13TP57524,224A*03/A*30/B*35/B*57/C*04/C*07
    14TP41623,279A*68/A*74/B*14/B*57/C*07/C*08
    15TP5009,333A*02/A*32/B*08/B*55/C*03/C*07
    Median44039,550
  • a VC, viremic controller; EC, elite controller; TP, typical progressor; DP, delayed progressor. DP refers to an individual who previously was a controller and later progressed. At the time of study, this individual had a viral load > 10,000 copies/ml compared to that determined for the prior year.

  • b Data represent CD4 counts within 4 weeks of sample collection.

  • c Data represent viral loads on the day of sample collection for assays (progressors were defined as having a median viral load >10,000 in the past year).

  • d B*27 and B*57 alleles are shown in bold. ND, not determined.