TABLE 3

Antiviral activity of filtered supernatants of IBRS-2 cells after treatment with Ad5-poIRF7/3(5D) in the presence or absence of IFN-neutralizing treatmenta

TreatmentIFN concn (U/ml)
B18R and anti-IFN-α negativeB18R and anti-IFN-α positive
Ad5-poIRF7/3(5D)11.30.0
Medium0.00.0
Ad5-Blue0.00.0
  • a The bioassay for antiviral activity was performed in supernatants of IBRS-2 cells collected 24 h after infection with Ad5-poIRF7/3(5D) in the presence or absence of IFN-neutralizing agents (B18R and anti-porcine IFN-α antibody).