TABLE 6

ICP4 mutations in attenuated viruses

VirusAmino acid change% frequency
Rep 1 p75L47P2.02
I228V2.16
C844R7.13
L2163P4.71
Rep 1 p85L47P2.99
I228V3.70
C844R9.26
L2163P9.25
Rep 2 p65G62V83.76
T195A39.76
Rep 3 p75Q63H100.00
L256S65.94
Y271C3.14
D1483V2.22
S1630P85.70
Md5 strain p61Y60C96.70
Y271C6.87
1631a8.14
H1670R2.77
  • a Indicates synonymous mutation.