Table 1

Specific infectivities of dengue virus, hepatitis C virus, and poliovirus in the absence and presence of spautin-1

VirusSpautin-1 concn (μM)Specific infectivitya
ExtracellularIntracellular
Dengue virus044 ± 8572 ± 120
124 ± 2676 ± 94
214 ± 31,450 ± 445
55 ± 413 ± 5
100.8 ± 0.10.1 ± 0.07
Hepatitis C virus048 ± 700.3 ± 0.4
163 ± 920.4 ± 0.2
541 ± 591.2 ± 1.3
1040 ± 450.5 ± 1
Poliovirus07 ± 1100 ± 75
15 ± 6130 ± 110
52 ± 286 ± 5
103 ± 462 ± 40
  • a For dengue virus, FFU/106 RNA molecules; for HCV, FFU/104 RNA molecules; for poliovirus, PFU/104 RNA molecules.