Table 2

Increased frequencies of reactivation, MHV68-genome-positive cells, persistent infection, and reactivation efficiency in PECs from PML−/− mice at 42 days postinfection

Mouse strainFrequency of reactivationFrequency of genome-positive cellsReactivation efficiency (%)bFrequency of persistent infection
PML−/−1/29,849 (1/25,319, 1/34,380)a1/848 (1/619, 1/1,078)a2.84%1/351,445 (1/238,334, 1/464,556)a
PML+/+1/84,050 (1/68,665, 1/99,435)a1/1,316 (1/958, 1/1,673)a1.57%1/2,827,263 (1/352,524, 1/5,302,002)a
Fold increase2.8 (P < 0.001)1.55 (P = 0.03)1.88 (P < 0.001)
  • a Values in parentheses are upper and lower limits (95% confidence intervals).

  • b Reactivation efficiency (%) = (frequency of reactivation/frequency of genome-positive cells) × 100.