Table 2

Reactivities of N1 MAbs with the NA of H1N1 and H5N1 viruses

MAb groupMAbIsotypeReactivity with N1 of the indicated virusa
BR/07NIH/09TX/91NC/99SI/06BM/18CA/09VN/04
A1C4IgG2b++
2D12IgG1++
3A2IgG2a++
4D6IgG2b++
4G2IgG1++
B1H5IgG2b++++++++
2D9IgG2b++++++++
2G6IgG2b++++++++
3H10IgG2b++++++++
4E9IgG2b++++++++
C1C7IgG2a+++±
2C3IgG2b++±++
2F4IgG2a++±++
3C2IgG1+++++
3G1IgG3+±±±±
D2B4IgG2a++±+++
2B5IgG2a+++++±
3C6IgG2a++++++
3H4IgG2b++±+++
E1C9IgG2a++++++±
1H8IgG2b++++++±
2D4IgG2b+++++++
3H3IgG2b+++++++
4B12IgG2b+++++++
F4C4IgG2a++++++
  • a Values were determined in ELISAs with H1N1 viruses A/Brisbane/59/2007 (BR/07), A/Texas/36/1991 (TX/91), A/New Caledonia/20/1999 (NC/99), A/Solomon Islands/3/2006 (SI/06), and A/California/07/2009 (CA/09)-X179A and the NA of A/Bethesda/NIH50/2009 (NIH/09), A/Brevig Mission/1/1918 (BM/18), and A/Vietnam/1203/2004 (VN/04) expressed on HEK293 cells. +, OD490 of >0.3; −, OD490 of <0.15; ±, OD490 value between 0.15 and 0.30.