Table 1

Immunogenicity of sciIV in mice

TreatmentCollection timeaSerum GMTb
HAI± SD
PBSPrime + boost<20ND
pH1N1/E3-sciIVPrime only2956
Prime + boost660750
pH1N1/E3-sciIV, UV inactivatedPrime + boost<20ND
Convalescent-phase serac2,100780
  • a Vaccinations were administered at 2 week intervals; samples were collected 2 weeks after the indicated dose.

  • b Data were calculated from 10 immunized or 2 convalescent individual animals. ND, not determined.

  • c Mice were inoculated with a nonlethal dose of pH1N1/E3; sera were collected 2 weeks later.