Table 1

Mutations in clone 2 relative to parental J6/JFH-1 virus

HCV proteinAmino acid in polyprotein
CoreK78E
E1I374L
E2I411V
NS2E863G
NS2V881G
NS3P1620S
NS3E1638D
NS5AL2266P
NS5AL2344F
NS5AQ2346P
NS5AA2348V
NS5BP2577S