Table 3

AP33 residues in close proximity to E2 peptide 8741

AP33 residueNo. of contacts with peptide 8741aBuried surface area (%)b
H chain
L chain
  • a Atomic intermolecular contacts between AP33 Fab residues and the E2 epitope peptide 8741 were determined using the software program CONTACT, as implemented in the CCP4 suite (54). Atoms within 4.5 Å of each other were considered to be in contact.

  • b Percent surface area of the AP33 residue that becomes buried upon complex formation with the peptide. Buried surface areas were calculated by the software program PISA (33).