Table 2

Summary of epitopes differentially targeted by HLA-B*5702, B*5703 and B*5801

ProteinEpitopea
B*5702B*5703B*5801
p17LVWASRELERFb
ISPRTLNA WbISPRTLNA W
KAFSPEVIPMF
p24DTINEEAAE Wb
TSTLQEQIA WbTSTLQEQIA WTSTLQEQIA W
QATQDVKN WbQATQDVKN WQATQDVKN Wb
RTFSVPLDEG FbFSVPLDEG Fb
IAMESIVI WbIAMESIVI WIAMESIVI Wb
QATWIPEWE FbQATWIPEWE Fb
INTSAAVKAAC Wb
KTAVQMAV FKTAVQMAV Fb
NEFKAAFDLSF FbKAAFDLSF FbKAAFDLSF Fb
HTQGFFPD WHTQGFFPD Wb
RevQAVRIIKIL YQAVRIIKIL Y
VIFLGHGVSIE Wb
EnvTVYYGVPV WbTVYYGVPV Wb
KAYEKEVHNVWKAYEKEVHNVW
  • a Selection of escape mutations is indicated by boldface.

  • b New epitopes not listed in the Los Alamos “A” list database.