Table 3.

Glycans considered to be bound significantly by pseudorevertant viruses on sialo-derivative glycan arraysa

Virus and print IDGlycan structureMeanSD%CV
WT rH3N1
    79Galβ4GlcNAcβ2Manα3(Galβ4GlcNAcβ2Manα6)Manβ4GlcNAcβ4GlcNAcitol-AEABb3,124241
    45Neu5Ac9Ltα6Galβ4GlcNAcβ2Manα3(Neu5Ac9Ltα6Galβ4GlcNAcβ2Manα6)Manβ4GlcNAcβ4GlcNAcitol-AEAB1,97130215
    12Neu5Ac9Ltα6Galβ4GlcNAcβ3Galβ4Glcitol-AEAB1,36436527
    48Neu5Acα3Galβ4GlcNAcβ2Manα3(Neu5Acα3Galβ4GlcNAcβ2Manα6)Manβ4GlcNAcβ4GlcNAcitol-AEAB1,29213911
    35Neu5Acα6Galβ4GlcNAcβ2Manα3(Neu5Acα6Galβ4GlcNAcβ2Manα6)Manβ4GlcNAcβ4GlcNAcitol-AEAB1,12223321
Y98F/S145I
    48Neu5Acα3Galβ4GlcNAcβ2Manα3(Neu5Acα3Galβ4GlcNAcβ2Manα6)Manβ4GlcNAcβ4GlcNAcitol-AEAB2042814
    74Neu5,9Ac2α3Galβ3GlcNAcβ3Galβ4Glcitol-AEAB1925730
    65Kdn5Meα6Galβ3GlcNAcβ3Galβ4Glcitol-AEAB1012020
Y98F/K238N
    74Kdn5Meα6Galβ3GlcNAcβ3Galβ4Glcitol-AEAB87116118
    65Neu5,9Ac2α3Galβ3GlcNAcβ3Galβ4Glcitol-AEAB4276816
    2Neu5Ac8Meα6Galβ4GlcNAcβ3Galβ4Glcitol-AEAB1884926
    49Neu5Ac8Meα3Galβ4GlcNAcβ2Manα3(Galβ4GlcNAcβ2Manα6)Manβ4GlcNAcβ4GlcNAcitol-AEAB1692817
  • a Significant binding was considered to be 2 times the background average, with a %CV of <50%.

  • b AEAB, 2-amino-N-(2-aminoethyl)benzamide.