Table 3.

Neutralization of PBMC-grown primary isolates by immune rabbit seraa

Table 3.
  • a All animals were primed with clade C gp120 DNA and boosted with the V3-CTB immunogen(s). Data shown are the reciprocals of GMT50 values for responding animals in each group. Responding animals are defined as those with sera that display 50% neutralization with a reciprocal titer of ≥10. Parentheses in each box indicate the number of responding animals over the number of animals immunized in each group. Values are color coded: red, GMT50−1 > 1,000; orange, 100 to 999; yellow, 10 to 99; white, <10. *, percent neutralization by pool of five anti-V3 MAbs used at a final concentration of 50 μg/ml (10 μg/ml of each MAb). Data are pooled from 2 to 7 experiments.