Table 2.

Relative mRNA expression levels of chemokines (ligands and receptors) that affect multiple cell typesa

Ligand or receptorOther nameRelative mRNA expression in groupb:
TMEV infected/PBS (day 2 p.i.)Day 6 p.i.
Seizures/PBSNo seizures/PBSSeizures/no seizures
PMN and monocyte/macrophage recruitment
PMN recruitment and affects NK cells
Monocyte/macrophage recruitment and affects NK cells
PMN and monocyte/macrophage recruitment and affects NK cells
  • a CCL, chemokine (C-C motif) ligand; CCR, chemokine (C-C motif) receptor; CX3CL, chemokine (C-X3-C motif) ligand; CXCL, chemokine (C-X-C motif) ligand; CXCR, chemokine (C-X-C motif) receptor; IP-10, IFN-γ-inducible protein 10; MCP, monocyte chemoattractant protein; MDC, macrophage-derived chemokine; MIP, macrophage inflammatory protein; MRP-1, MIP-related protein 1; NK, natural killer; PBS, phosphate-buffered saline; PF-4, platelet factor 4; p.i., postinfection; PMN, polymorphonuclear leukocyte; RANTES, regulated on activation, normal T-cell expressed and secreted; SDF-1, stromal cell-derived factor 1; TMEV, Theiler's murine encephalomyelitis virus.

  • b mRNA expression normalized to normal-brain control group.