TABLE 3

Neutralization of 10E8 variants on a 200-or 203-isolate panela

10E8 or variantTotal no. of viruses in panelNo. of viruses neutralized at IC50 (IC80) of:% of viruses neutralized at IC50 (IC80) of:Median IC50 (IC80)Geometric mean IC50 (IC80)
<50 μg/ml<10 μg/ml<1 μg/ml<0.1 μg/ml<0.01 μg/ml<50 μg/ml<10 μg/ml<1 μg/ml<0.1 μg/ml<0.01 μg/ml
10E8200195 (195)194 (186)145 (57)38 (9)9 (5)98 (98)97 (93)73 (29)19 (5)5 (3)0.392 (1.76)0.315 (1.52)
10E8v1200196 (195)195 (190)148 (57)53 (15)17 (6)98 (98)98 (95)74 (29)27 (8)9 (3)0.397 (2.03)0.228 (1.42)
10E8v4200196 (195)194 (181)143 (49)46 (11)13 (5)98 (98)97 (91)72 (25)23 (6)7 (3)0.435 (2.50)0.276 (1.94)
10E8v5200196 (195)194 (185)146 (51)42 (11)12 (6)98 (98)97 (93)73 (26)21 (6)6 (3)0.418 (2.07)0.307 (1.70)
10E8v4203198 (198)198 (185)146 (54)39 (10)11 (3)98 (98)98 (91)72 (27)19 (5)5 (1)0.428 (2.23)0.329 (1.67)
10E8v4-DS203171 (146)148 (125)93 (40)29 (7)11 (3)84 (72)73 (62)46 (20)14 (3)5 (1)0.706 (2.41)0.641 (2.06)
  • a Numbers in parentheses are results for IC80.