TABLE 2

Comparison of magnitude of neutralizing titers by generalized linear model analysis

VaccineEstimateaSEt valuePr(>|z|)
Comparison across Tier 1A pseudovirions to 4C mixture
3C1.6720.227−0.9823.260e−01
2C1.7750.226−1.1012.707e−01
459C2.7250.183−2.3751.755e−02b
405C6.0300.213−3.6642.485e−04b,c
939C36.980.198−7.9032.722e−15b,c
C97ZA01216.160.163−7.4111.250e−13b,c
Comparison across Tier 1B pseudovirions to 4C mixture
3C0.6810.1381.2012.297e−01
2C1.7230.123−1.9195.500e−02
459C1.2280.105−0.8423.992e−01
405C2.7240.118−3.6992.168e−04b,c
939C2.9030.117−3.9687.258e−05b,c
C97ZA0122.7040.093−4.6403.501e−06b,c
Comparison across Tier 1A pseudovirions to 459C
4C0.3850.1812.2902.200e−02b
3C0.6350.2180.9033.665e−01
2C0.6860.2170.7544.506e−01
405C2.2990.204−1.7737.623e−02
939C14.230.189−6.0981.075e−09b,c
C97ZA0126.0820.153−5.1412.729e−07b,c
Comparison across Tier 1B pseudovirions to 459C
4C0.8140.1060.8433.991e−01
3C0.5540.1371.8666.204e−02
2C1.4030.121−1.2132.250e−01
405C2.2190.116−2.9912.780e−03b,c
939C2.3640.115−3.2591.119e−03b,c
C97ZA0122.2020.091−3.7831.549e−04b,c
  • a The “Estimate” column shows how much larger the comparison vaccine (4C or 459C) is, on average, than the vaccine in the left column.

  • b Significant by pairwise comparisons (P < 0.05).

  • c Significant after Bonferroni correction.