TABLE 1

Comparison of magnitudes of geometric means of neutralizing titers across test pseudovirions and by animalc

TestComparisonP value
Kruskal-WallisAll pseudovirions3.58E−07
Mann-Whitney U4C ≅ 3C0.42957
4C > 2C0.01998a
4C > 459C0.0007a,b
4C > 405C0.0045a,b
4C > 939C0.00033a,b
4C > C97ZA0125.10E−07a,b
Kruskal-WallisTier 1B pseudovirions1.40E−06
Mann-Whitney U4C ≅ 3C0.5704
4C > 2C0.050a
4C > 459C0.0007a,b
4C > 405C0.012a
4C > 939C0.0003a,b
4C > C97ZA0125.10E−07a,b
Kruskal-WallisAll pseudovirions0.0022
Mann-Whitney U459C > 405C0.038a
459C > 939C0.00033a,b
459C > C97Z3.57E−06a,b
Kruskal-WallisTier 1B pseudovirions0.0073
Mann-Whitney U459C > 405C0.028a
459C > 939C0.0013a,b
459C > C97Z3.57E−06a,b
  • a Significant by pairwise comparisons (P < 0.05).

  • b Significant after Bonferroni correction.

  • c 4C is compared to all vaccination regimens and 459C to the single-strain vaccines.