TABLE 2

Amino acid substitutions in rH5N3 genes after six serial passages in White Leghorn chickensa

Virus passageSubstitution in rH5N3 genes
PB2 (aa 466)PB1 (aa 633)PA (aa 263)HA (aa 387)NP (aa 371)NAM1 (aa 97)NS1 (aa 193)NEP
aa 82aa 293aa 329aa 36aa 52
P0DSTNMERAVREM
P1DSTNTGRAVREM
P2DRTNTGKAVRET
P3DRTDTGKTVRET
P4DRTDTGKTIRET
P5NRKDTGKTIQKT
P6NRKDTGKTIQKT
  • a aa, amino acid.