TABLE 1

Total numbers of transcripts affected by infection with wt EBOV or the mutated viruses or by treatment with LPSa

Time pointFold change over mock infectionNo. of upregulated transcriptsNo. of downregulated transcripts
wt EBOVEBOV/VP35 mEBOV/VP24 mEBOV/VP35 m/VP24 mLPSwt EBOVEBOV/VP35 mEBOV/VP24 mEBOV/VP35 m/VP24 mLPS
8 h463/29561/29719/1492/169255/2571/046/100/085/3781/67
161/4128/500/092/2212/60/00/00/02/011/0
640/061/190/041/61/00/00/00/00/00/0
24 h4413/343639/456639/456935/977N/A134/62462/348219/34516/425N/A
1677/47262/232136/85294/271N/A7/150/324/066/42N/A
6427/3134/9558/14160/131N/A0/016/120/017/11N/A
  • a The numbers of upregulated or downregulated transcripts in DC from the two donors are separated by slashes (donor 1/donor 2).