TABLE 2.

Cell cycle distribution of latently infected cells

Patient no.Cell cycle stageFrequency of infected cells/106 cells% of B cells% of infected B cellsa
1G0/G114,0009795
S/G2/M26,0002.85
2G0/G19009897
S/G2/M1,4002.23.4
3G0/G114,0009190
S/G2/M16,000910
  • a The percentage of infected B cells was calculated from the data in columns 3 and 4, e.g., for patient 1, for every 106 B cells; 97% are in G0/G1 and the frequency of infected cells is 14,000/106 cells. This is equal to 0.97 × 106 G0/G1 B cells with 13,800 infected cells, and 2.8% are in S/G2/M and the frequency of infected cells is 26,000/106 cells. This is equal to 0.028 × 106 S/G2/M B cells with 730 infected cells. The total number of infected cells is 13,800 plus 730, which equals 14,530 cells. The percentage of cells in G0/G1 is 13,800 × 100/14,350, which equals 95%, and the percentage of cells in S/G2/M is 730 × 100/14,350, which equals 5%.