TABLE 1.

Characterized and partially characterized dengue virus receptor proteins

Cell typeSpeciesSerotypeReceptor characteristicsReference(s)
VeroKidney (simian)D1Protein31
HepG2Hepatocyte (human)D1Protein31
MacrophageHumanD2Proteins (27, 45, 67, 87 kDa)33
CHOOvary (hamster)D2Glycosaminoglycan10, 17
BHKKidney (hamster)D2Glycosaminoglycan23
VeroKidney (simian)D2Glycosaminoglycan10, 17
MonocytesHumanD2FcR, protein11, 14
MonocytesHumanD2CD14-associated molecule12
HepG2Hepatocyte (human)D2GRP7825
K562Bone marrow (human)D2Protein (100kDa)39
HL60Myelomonocyte (human)D2, D3Proteins (∼40, ∼70kDa), GAGsa3
RajiB cell (human)D2, D3Proteins (∼34, ∼45, ∼72 kDa)4
Molt4T cell (human)D2, D3Proteins (∼34, ∼45, ∼72kDa)4
LK63B cell (human)D2, D3Proteins (∼34, ∼45, ∼72kDa)4
C6/36Whole larva (mosquito)D4Proteins (40, 45 kDa)40
VeroKidney (simian)D4Proteins (44, 74 kDa)32
Dendritic cellsMonocyte derived (human)D1-4ICAM3-grabbing nonintegrin34
  • a GAG, glycosaminoglycans.