TABLE 1.

HCMV proteins identified by LC-MS/MS and/or by FTICR from virions and dense bodies

Viral protein groupHCMV ORFLC-MS/MSFTICR% Cov- erage
No. of different peptidesMax XCorrNo. of different peptides
Virion proteins
    CapsidUL46205.301444.8
UL48-4986.52554.7
UL80376.363035.6
UL85216.732263.1
UL861493.9712371.0
    TegumentUL2485.06938.3
UL25607.045959.2
UL2694.771053.7
UL321353.0110070.5
UL4375.501028.1
UL47536.106457.5
UL481114.2910956.8
UL82706.394769.3
UL831235.448692.0
UL94105.081226.4
UL9985.87964.7
US2223.1625.4
US2312.6114.6
US2414.8327.0
    GlycoproteinsRL1052.36422.8
TRL14 *a17.5
UL5 *15.4
UL22A15.04119.4
UL3346.11414.1
UL38 *15.7
UL41A25.72225.6
UL5012.82410.6
UL55216.162324.8
UL7323.4726.5
UL7445.07413.5
UL75216.152235.7
UL77145.651231.2
UL93155.351431.7
UL100135.24715.9
UL115114.73947.1
UL11922.2314.6
UL13285.89847.0
US2744.2527.7
    Transcription-repli- cation machineryIRS1156.011725.8
TRS1106.922334.7
UL4414.32931.0
UL45435.855252.2
UL54*11.6
UL57*10.4
UL6964.17719.0
UL72*14.6
UL8412.50312.8
UL89*13.1
UL97135.95932.1
UL12224.26411.7
    UncharacterizedUL35426.274056.1
UL51*13.2
UL71126.321140.4
UL79*110.9
UL88146.81733.6
UL9614.46119.7
UL10385.18837.0
UL10494.68923.0
UL11213.3044.7
Dense body proteins
    CapsidUL4613.66
UL48-4925.81
UL8016.12
UL8545.04
UL86225.019
    TegumentUL25176.313
UL2633.63
UL32115.415
UL3555.69
UL4724.36
UL4875.412
UL8295.16
UL83406.314
UL7545.62
    Transcription-repli- cation machineryUL4524.36
IRS135.62
TRS114.75
  • a Asterisks indicate proteins whose LC-MS/MS SEQUEST scores were lower than our cutoff values; however, the proteins were identified with the more sensitive FTICR.