TABLE 1.

Antigenic characterization of outer capsid glycoprotein VP7 of selected G9 rotavirus strains belonging to VP7 gene phylogenetic sequence lineage 1, 2, or 3

StrainRotavirus characteristicsReciprocal of 60% PRN antibody titer of guinea pig hyperimmune antiserum to indicated rotavirus reassortant (VP7 gene lineage)b
Country of originYear collectedTypeE typeaVP7 gene lineageUK × WI61 (1)UK × WI61 (1)UK × AU32 (1)UK × AU32 (1)UK × 116E (2)UK × 116E (2)UK × R44 (3)UK × R44 (3)UK × R143 (3)UK × R143 (3)UK × US1205 (3)UK × US1205 (3)UK × INL1 (3)UK × INL1 (3)UK × BD524 (3)UK × BD524 (3)
PG
WI61U.S.1983[8]9L120,48020,48020,48040,9601,28016080<80640640<8080<8080<80160
DS-1 × WI61 reassortant[4]9S110,24020,48020,48040,960640160160<80640640<80<80808080160
F45Japan1985[8]9L110,24040,96040,96040,9605,1202,5606402,5602,5605,1206403202,5602,5603205,120
AU32Japan1986[8]9L140,96040,96081,92081,9205,1202,5601,2802,5602,5602,5603203202,5602,5606405,120
116EIndia1986[11]9L210,24010,24020,48020,48020,48010,2406406402,5602,5606406401,2802,5606402,560
R44Brazil1997[9]9L340,96020,48040,96040,96010,24010,24010,24020,48040,96081,92010,24010,24020,48081,92040,96040,960
R143Brazil1999[6]9S340,96020,48081,92081,92020,48010,24020,48020,48081,92081,92010,24020,48020,48040,96040,96081,920
US1205U.S.1996-1997[6]9S340,96020,48040,96040,96010,24010,24010,24010,24040,96081,92020,48010,24020,48040,96081,92081,920
INL1India1994[6]9L340,96010,24081,92081,92010,24020,48010,24020,48081,92081,92020,48020,48040,96081,92040,96081,920
BD524Bangladesh1995-1996[8]9L310,24010,24010,24010,24010,24010,24010,24010,24040,96081,92010,24010,24040,96081,92040,960>81,920
UKUKd1975[5]6LNAc2,5606403206403206406406401606406403206406402,560640
  • a Antigenic characterization for strains was done by analysis of their guinea pig hyperimmune antiserum neutralization profile. E type; electropherotype; L, long; S, short.

  • b The homologous 60% PRN antibody titers ranged from 20,480 to >81,920 in previous tests in this laboratory. Values belonging to the same VP7 gene sequence lineage are in boldface type. VP7 homologous values are underlined.

  • c NA, not applicable.

  • d United Kingdom.