TABLE 2.

Virus titers in B6 mice infected with a high dose (108 PFU) of WNVa

Days p.i.SerumBrainLiverSpleenLNThymus
1<1021.0 × 1055.0 × 1041.0 × 1046.0 × 1041.5 × 103
<1022.0 × 1045.0 × 1045.0 × 1047.2 × 1043.2 × 103
<1023.8 × 1046.8 × 1042.0 × 1049.0 × 1036.8 × 103
<1027.3 × 1033.2 × 1041.0 × 1044.3 × 1045.2 × 103
<102<1034.7 × 1047.7 × 104<103<103
2<1022.0 × 1055.0 × 1031.5 × 1032.2 × 1036.5 × 103
<1021.5 × 1045.0 × 1041.5 × 1038.5 × 1035.4 × 103
<1029.2 × 1042.9 × 1042.0 × 1046.0 × 1041.3 × 103
<1026.8 × 1051.0 × 1057.0 × 1031.5 × 104<103
<1023.8 × 1053.2 × 1045.0 × 104<103<103
3<1021.7 × 1075.0 × 1045.0 × 1045.0 × 1035.0 × 103
<1021.0 × 1071.2 × 1033.5 × 1033.0 × 1041.8 × 103
<1027.6 × 1072.0 × 1045.2 × 1039.5 × 1033.0 × 103
<1023.9 × 105<1031.2 × 1034.4 × 103<103
<1025.3 × 107<103<103<103<103
4<1021.2 × 1091.2 × 1036.0 × 1044.5 × 103<103
<1023.0 × 1083.2 × 1031.2 × 1032.7 × 103<103
<1027.2 × 108<103<1031.4 × 103<103
<1025.0 × 108<103<103<103<103
<1021.1 × 109<103<103<103<103
5<1023.2 × 108<103<1032.0 × 103<103
<1022.5 × 108<103<1032.7 × 103<103
<1021.1 × 109<103<1034.2 × 103<103
<1027.9 × 108<103<103<103<103
<1022.0 × 108<103<103<103<103
6<1022.0 × 108<103<103<103<103
<1023.7 × 107<103<103<103<103
<1026.9 × 107<103<103<103<103
  • a Values are given as PFU per milliliter of serum, PFU per gram of tissue, and PFU per lymph node (LN). Viral titers were determined by Vero cell plaque assay. The limit of detection was 102 PFU/ml for serum, 103 PFU/g for tissue, or 103 PFU/LN.